Genomic Applications in Pathology

  • George Jabboure Netto
  • Karen L. Kaul

Table of contents

  1. Front Matter
    Pages i-xx
  2. Genomic Technologies

    1. Front Matter
      Pages 1-1
    2. Matthew W. Anderson
      Pages 23-31
    3. Jacquelyn Reuther, Angshumoy Roy, Federico A. Monzon
      Pages 33-49
    4. Cornelia Braicu, Diana Gulei, Beatriz de Melo Maia, Ioana Berindan-Neagoe, George A. Calin
      Pages 51-71
    5. Dorraya El-Ashry, Marija Balic, Richard J. Cote
      Pages 73-87
    6. Natasha B. Hunter, Julia A. Beaver, Ben Ho Park
      Pages 89-99
  3. Practice-Related Aspects of Clinical Genomics

    1. Front Matter
      Pages 101-101
    2. Richard L. Haspel
      Pages 103-111
    3. Roger D. Klein
      Pages 127-134
    4. Henry T. Greely
      Pages 135-146
  4. Clinical Implementation of Diagnostic Genomics

    1. Front Matter
      Pages 147-147
    2. David K. Crockett, Karl V. Voelkerding, Alan F. Brown, Rachel L. Stewart
      Pages 163-182
    3. Hao Ho, Christopher D. Gocke
      Pages 183-190
    4. Michael O. Dorschner
      Pages 191-202
    5. Samya Chakravorty, Arunkanth Ankala, Madhuri R. Hegde
      Pages 203-217
    6. Tina M. Hambuch, Keith Nykamp, Carri-Lyn Rebecca Mead
      Pages 219-236
  5. Genomic Applications in Oncology

    1. Front Matter
      Pages 267-267
    2. Kevin E. Fisher, Linsheng Zhang, Charles E. Hill
      Pages 269-287
    3. Matija Snuderl
      Pages 289-308
    4. Joseph A. Bellairs, Jessica Yesensky, Jamie Ahn Ku, Nishant Agrawal
      Pages 309-324
    5. Thomas J. Giordano
      Pages 325-334
    6. Todd M. Stevens, Justin A. Bishop
      Pages 335-345
    7. Fresia Pareja, Leticia De Mattos-Arruda, Britta Weigelt, Jorge S. Reis-Filho
      Pages 347-361
    8. Reinhard Büttner, Carina Heydt, Sabine Merkelbach-Bruse
      Pages 363-392
    9. Lauren L. Ritterhouse, Wade S. Samowitz
      Pages 393-399
    10. Fátima Carneiro, Ralph H. Hruban
      Pages 401-418
    11. Martin J. Magers, Joshua I. Warrick, Scott A. Tomlins
      Pages 419-443
    12. Sarah Chiang, Luciano G. Martelotto, Britta Weigelt
      Pages 445-469
    13. Martin Köbel, James D. Brenton
      Pages 471-482
    14. Eva Wardelmann, Wolfgang Hartmann
      Pages 483-507
    15. Carlos N. Prieto-Granada, John Van Arnam, Kabeer K. Shah, Aleodor A. Andea, Alexander J. Lazar
      Pages 509-540
  6. Genomic Applications in Inherited and Infectious Diseases, Pharmacogenomics, and the Microbiome

    1. Front Matter
      Pages 541-541
    2. Bryan L. Krock, Rong Mao, Tatiana Tvrdik, D. Hunter Best, Elaine Lyon
      Pages 543-560
    3. Martina I. Lefterova, Carlos J. Suarez, Niaz Banaei, Benjamin A. Pinsky
      Pages 583-594
    4. Mohammad Omar Hussaini, Howard L. McLeod
      Pages 595-606
    5. Wyatt M. Arnold, Elle Simone Hill, Na Fei, Alyson L. Yee, Mariana Salas Garcia, Lauren E. Cralle et al.
      Pages 607-618
  7. Back Matter
    Pages 619-638

About this book


​This book provides the most up-to-date comprehensive discussion of established and emerging genomic technologies and their clinical implementation in molecular diagnostics.  As in its first edition, the book places significant emphasis on implementation roadmaps for various clinical assays including single gene, gene panel, transcriptome sequencing, circulating tumor cells and cell-free DNA sequencing, whole exome, and whole genome assays. Detailed guidance on the central role of the pathologist in the interpretation, reporting, and clinical integration of genomic tests is provided. Expert opinions to help navigate growing compliance, reimbursement, legal and ethical issues are shared in dedicated chapters.

Genomic Applications in Pathology provides a comprehensive resource for practicing molecular pathologists, general and sub-specialized practicing anatomic and clinical pathologists, as well as pathology trainees. The wider target audience continues to include oncologists, geneticists, and other medical and surgical clinicians.


Circulating Tumor Cells Clinical Genomics Genomic Medicine Pharmacogenomics RNAseq Sequencing Assays miRNA Assays

Editors and affiliations

  • George Jabboure Netto
    • 1
  • Karen L. Kaul
    • 2
  1. 1.Professor and Chair of PathologyUniversity of Alabama at BirminghamBirminghamUSA
  2. 2.Department of Pathology and Laboratory Medicine, NorthShore University HealthSystem, Clinical Professor of PathologyUniversity of Chicago Pritzker School of MedicineEvanstonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-96829-2
  • Online ISBN 978-3-319-96830-8
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals