Bioinformatics and Biomedical Engineering

1. Front Matter

   Pages I-XXXI

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2. Bioinformatics for Healthcare and Diseases

   1. Front Matter

      Pages 1-1

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   2. Trends in Online Biomonitoring

      • Antonín Bárta, Pavel Souček, Vladyslav Bozhynov, Pavla Urbanová, Dinara Bekkozhayeova

      Pages 3-14

   3. SARAEasy: A Mobile App for Cerebellar Syndrome Quantification and Characterization

      • Haitham Maarouf, Vanessa López, Maria J. Sobrido, Diego Martínez, Maria Taboada

      Pages 15-25

   4. Case-Based Reasoning Systems for Medical Applications with Improved Adaptation and Recovery Stages

      • X. Blanco Valencia, D. Bastidas Torres, C. Piñeros Rodriguez, D. H. Peluffo-Ordóñez, M. A. Becerra, A. E. Castro-Ospina

      Pages 26-38

3. Bioinformatics Tools to Integrate Omics Dataset and Address Biological Question

   1. Front Matter

      Pages 39-39

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   2. Constructing a Quantitative Fusion Layer over the Semantic Level for Scalable Inference

      • Andras Gezsi, Bence Bruncsics, Gabor Guta, Peter Antal

      Pages 41-53

4. Challenges and Advances in Measurement and Self-Parametrization of Complex Biological Systems

   1. Front Matter

      Pages 55-55

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   2. Effects of External Voltage in the Dynamics of Pancreatic β-Cells: Implications for the Treatment of Diabetes

      • Ramón E. R. González, José Radamés Ferreira da Silva, Romildo Albuquerque Nogueira

      Pages 57-70

   3. ISaaC: Identifying Structural Relations in Biological Data with Copula-Based Kernel Dependency Measures

      • Hossam Al Meer, Raghvendra Mall, Ehsan Ullah, Nasreddine Megrez, Halima Bensmail

      Pages 71-82

   4. Inspecting the Role of PI3K/AKT Signaling Pathway in Cancer Development Using an In Silico Modeling and Simulation Approach

      • Pedro Pablo González-Pérez, Maura Cárdenas-García

      Pages 83-95

   5. Cardiac Pulse Modeling Using a Modified van der Pol Oscillator and Genetic Algorithms

      • Fabián M. Lopez-Chamorro, Andrés F. Arciniegas-Mejia, David Esteban Imbajoa-Ruiz, Paul D. Rosero-Montalvo, Pedro García, Andrés Eduardo Castro-Ospina et al.

      Pages 96-106

   6. Visible Aquaphotomics Spectrophotometry for Aquaculture Systems

      • Vladyslav Bozhynov, Pavel Soucek, Antonin Barta, Pavla Urbanova, Dinara Bekkozhayeva

      Pages 107-117

   7. Resolution, Precision, and Entropy as Binning Problem in Mass Spectrometry

      • Jan Urban

      Pages 118-128

   8. Discrimination Between Normal Driving and Braking Intention from Driver’s Brain Signals

      • Efraín Martínez, Luis Guillermo Hernández, Javier Mauricio Antelis

      Pages 129-138

   9. Unsupervised Parametrization of Nano-Objects in Electron Microscopy

      • Pavla Urbanová, Norbert Cyran, Pavel Souček, Antonín Bárta, Vladyslav Bozhynov, Dinara Bekkhozhayeva et al.

      Pages 139-149

5. Computational Genomics

   1. Front Matter

      Pages 151-151

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   2. Models of Multiple Interactions from Collinear Patterns

      • Leon Bobrowski, Paweł Zabielski

      Pages 153-165

   3. Identification of the Treatment Survivability Gene Biomarkers of Breast Cancer Patients via a Tree-Based Approach

      • Ashraf Abou Tabl, Abedalrhman Alkhateeb, Luis Rueda, Waguih ElMaraghy, Alioune Ngom

      Pages 166-176

   4. Workflows and Service Discovery: A Mobile Device Approach

      • Ricardo Holthausen, Sergio Díaz-Del-Pino, Esteban Pérez-Wohlfeil, Pablo Rodríguez-Brazzarola, Oswaldo Trelles

      Pages 177-185

This two-volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.
The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

• computational genomics
• computational proteomics
• health informatics
• systems biology
• health care information systems
• bioinformatics
• life and medical sciences
• biomedical engineering
• medical technologies
• computational biology
• metabolomics / metabonomics
• recognition of genes and regulatory elements
• Artificial intelligence
• image processing
• machine learning
• semantics
• Support Vector Machines
• internet
• computer networks
• world wide web

• University of Granada, Granada, Spain

  Ignacio Rojas, Francisco Ortuño

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