Dermal Drug Selection and Development

An Industrial Perspective

  • Lionel Trottet
  • Howard Maibach, MD

Table of contents

  1. Front Matter
    Pages i-xv
  2. Lionel Trottet, Howard Maibach
    Pages 1-13
  3. Lionel Trottet, Howard Maibach
    Pages 15-28
  4. Lionel Trottet, Howard Maibach
    Pages 39-48
  5. Lionel Trottet, Howard Maibach
    Pages 49-67
  6. Lionel Trottet, Howard Maibach
    Pages 69-86
  7. Lionel Trottet, Howard Maibach
    Pages 87-93
  8. Lionel Trottet, Howard Maibach
    Pages 95-107
  9. Lionel Trottet, Howard Maibach
    Pages 109-113
  10. Lionel Trottet, Howard Maibach
    Pages 115-131
  11. Lionel Trottet, Howard Maibach
    Pages 139-143
  12. Back Matter
    Pages 145-148

About this book

Introduction

The authors show how the pharmaceutical industry faces the development of dermal drugs and provide the only book of its kind that describes how the industry develops and selects dermal drugs, complete with the challenges and opportunities of the field. Delivery of drugs through the skin has been an attractive and challenging area for research, and advances in modern technologies have resulted in a larger number of drugs being delivered transdermally, including conventional hydrophobic small molecule drugs, hydrophilic drugs and macromolecules. Offering the perspective from the industrial side of selection and development of drugs, the primary audience is geared towards the pharmaceutical industry but can also offer valuable information to clinicians, compounding pharmacists, and similarly pharmacy students. Dermal Drug Selection and Development covers the

scientific gaps that exist in terms of dermal pharmacokinetics and the resulting uncertainty by clinicians when choosing a drug candidate.

Keywords

drug development dermal pharmacokinetics dermal drugs dermal drug candidate selection dermatology

Authors and affiliations

  • Lionel Trottet
    • 1
  • Howard Maibach, MD
    • 2
  1. 1.OncodesignCentre de Recherches François HyafilVillebon sur YvetteFrance
  2. 2.Dermatology Department, Medical SchoolUniversity of CaliforniaSan FranciscoUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-59504-7
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-59503-0
  • Online ISBN 978-3-319-59504-7
  • About this book
Industry Sectors
Chemical Manufacturing
Biotechnology
Consumer Packaged Goods
Pharma