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Pharmacologic Therapy of Ocular Disease

  • Book
  • © 2017

Overview

Editors:
  1. Scott M. Whitcup

    1. Akrivista and Whitecap Biosciences, Mission Viejo, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Dimitri T. Azar

    1. Illinois Eye and Ear Infirmary, University of Illinois at Chicago College of Medicine, Chicago, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Current review of the basic principles of ocular pharmacology, pharmacokinetics, and drug delivery including novel approaches to delivering compounds to the eye like sustained-release implants, cell therapy, and gene therapy
  • Review of existing and future therapies for ocular diseases from the eye lids to the optic nerve
  • Discussion of potential adverse effects of pharmacologic treatments and limitationof side effects in the treatment of ocular disease
  • Includes supplementary material: sn.pub/extras
  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 242)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-viii
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  2. Principles of Ocular Pharmacology

    • Yong Park, Dorette Ellis, Brett Mueller, Dorota Stankowska, Thomas Yorio
    Pages 3-30

  3. Ocular Pharmacokinetics

    • Chandrasekar Durairaj
    Pages 31-55

  4. Ocular Drug Delivery

    • Burcin Yavuz, Uday B. Kompella
    Pages 57-93

  5. Ocular Pharmacology of Tear Film, Dry Eye, and Allergic Conjunctivitis

    • Shilpa Gulati, Sandeep Jain
    Pages 97-118

  6. Anti-Infective and Anti-Inflammatory Pharmacotherapies

    • Mark I. Rosenblatt
    Pages 119-135

  7. Keratoconus and Other Corneal Diseases: Pharmacologic Cross-Linking and Future Therapy

    • Kimberly M. Hsu, Joel Sugar
    Pages 137-161

  8. Lens: Management of Cataract Surgery, Cataract Prevention, and Floppy Iris Syndrome

    • Joao Crispim, Wallace Chamon
    Pages 163-178

  9. Glaucoma-Intraocular Pressure Reduction

    • Alex S. Huang, Lilit Minasyan, Robert N. Weinreb
    Pages 181-207

  10. Translational Pharmacology in Glaucoma Neuroprotection

    • Leonard A. Levin
    Pages 209-230

  11. Pharmacologic Treatment of Noninfectious Uveitis

    • Jared E. Knickelbein, Karen R. Armbrust, Meredith Kim, H. Nida Sen, Robert B. Nussenblatt
    Pages 231-268

  12. Anti-angiogenic Therapy for Retinal Disease

    • Yannis M. Paulus, Akrit Sodhi
    Pages 271-307

  13. Corticosteroids and Anti-Complement Therapy in Retinal Diseases

    • Raja Narayanan, Baruch D. Kuppermann
    Pages 309-320

  14. Dry Age-Related Macular Degeneration Pharmacology

    • Charles B. Wright, Jayakrishna Ambati
    Pages 321-336

  15. Hereditary Retinal Dystrophy

    • Thomas C. Hohman
    Pages 337-367

  16. Optic Nerve

    • Lynn K. Gordon
    Pages 369-386

  17. Back Matter

    Pages 387-394
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Keywords

About this book

There have been major advancements in the pharmacologic treatment of eye diseases over the past decade. With newly discovered disease targets and novel approaches to deliver therapeutic compounds to the eye, patients are seeing improved outcomes. Not only are there better treatments for diseases where treatments existed, we now have effective therapy for previously untreatable and blinding eye disorders. This volume will cover the pharmacologic treatment of eye diseases from the front of the eye including eyelids, conjunctiva and cornea all the way back to the retina and optic nerve. The first section of the volume reviews general principles of ocular pharmacology, pharmacokinetics, pharmaceutical sciences, and drug delivery. In addition, the volume provides an up to date guide to the pharmacologic approach to the key eye diseases that threaten sight or ocular function.

Editors and Affiliations

  • Akrivista and Whitecap Biosciences, Mission Viejo, USA

    Scott M. Whitcup

  • Illinois Eye and Ear Infirmary, University of Illinois at Chicago College of Medicine, Chicago, USA

    Dimitri T. Azar

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