Progress in the Chemistry of Organic Natural Products 104

  • A. Douglas Kinghorn
  • Heinz Falk
  • Simon Gibbons
  • Jun'ichi Kobayashi

Part of the Progress in the Chemistry of Organic Natural Products book series (POGRCHEM, volume 104)

Table of contents

  1. Front Matter
    Pages i-v
  2. Heinz Falk, Klaus Wolkenstein
    Pages 1-126
  3. Alejandra León, Mayela Del-Ángel, José Luis Ávila, Guillermo Delgado
    Pages 127-246

About this book

Introduction

The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis.
The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides.

Keywords

Molecular fossils Geological biomarkers Alkanes Aromatic compounds Phthalide Umbelliferae Bioactivity

Editors and affiliations

  • A. Douglas Kinghorn
    • 1
  • Heinz Falk
    • 2
  • Simon Gibbons
    • 3
  • Jun'ichi Kobayashi
    • 4
  1. 1.Division of Medicinal Chemistry & Pharmacognosy, College of PharmacyThe Ohio State UniversityColumbusUSA
  2. 2.Institute of Organic ChemistryJohannes Kepler University LinzLinzAustria
  3. 3.Research Department of Pharmaceutical and Biological ChemistryUCL School of PharmacyLondonUnited Kingdom
  4. 4.Graduate School of Pharmaceutical ScienceHokkaido UniversitySapporoJapan

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-45618-8
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-319-45616-4
  • Online ISBN 978-3-319-45618-8
  • Series Print ISSN 2191-7043
  • Series Online ISSN 2192-4309
  • About this book
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