Toxicology of Herbal Products

  • Olavi Pelkonen
  • Pierre Duez
  • Pia Maarit Vuorela
  • Heikki Vuorela

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Jandirk Sendker, Helen Sheridan
    Pages 11-27
  3. Jandirk Sendker, Helen Sheridan
    Pages 29-65
  4. Olavi Pelkonen, Jorma T. Ahokas
    Pages 67-80
  5. Danielle Sevior, Jorma Ahokas
    Pages 81-98
  6. Gert Laekeman
    Pages 99-127
  7. Alessandro Buriani, Stefano Fortinguerra, Maria Carrara, Olavi Pelkonen
    Pages 129-164
  8. Kati Hanhineva, Markku Pasanen
    Pages 165-178
  9. Mélanie Poivre, Amandine Nachtergael, Valérian Bunel, Okusa Ndjolo Philippe, Pierre Duez
    Pages 179-215
  10. Ean-Jeong Seo, Thomas Efferth
    Pages 217-235
  11. Jacqueline Wiesner
    Pages 237-269
  12. Chit Shing Jackson Woo, Hani El-Nezami
    Pages 271-305
  13. Thomas Baudoux, Joëlle L. Nortier
    Pages 307-344
  14. Pieter van der Bijl Jr., Pieter van der Bijl Sr.
    Pages 363-383
  15. Back Matter
    Pages 477-479

About this book


This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities.

With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.


Genotoxicity Herbal medicine Metabolomics Pharmacokinetics Teratogenicity Toxicity hazards

Editors and affiliations

  • Olavi Pelkonen
    • 1
  • Pierre Duez
    • 2
  • Pia Maarit Vuorela
    • 3
  • Heikki Vuorela
    • 4
  1. 1.Department of Pharmacology & ToxicologyUniversity of OuluOuluFinland
  2. 2.Service de Chimie Thérapeutique et de PharmacognosieUniversity of MonsMonsBelgium
  3. 3.Faculty of PharmacyUniversity of HelsinkiHelsinkiFinland
  4. 4.Faculty of PharmacyUniversity of HelsinkiHelsinkiFinland

Bibliographic information

Industry Sectors
Chemical Manufacturing
Consumer Packaged Goods