Environment and Skin

1. Front Matter

   Pages i-v

   PDF

2. Concepts and Methods

   1. Front Matter

      Pages 1-1

      PDF

   2. Barrier Skin

      • Hans F. Merk

      Pages 3-10

   3. Combined, Simultaneous Exposure to Radiation Within and Beyond the UV Spectrum: A Novel Approach to Better Understand Skin Damage by Natural Sunlight

      • Jean Krutmann, Kevin Sondenheimer, Susanne Grether-Beck, Thomas Haarmann-Stemmann

      Pages 11-16

   4. The Impact of Climate Change on Skin and Skin-Related Disease

      • Louise K. Andersen

      Pages 17-26

   5. Modern Skin Toxicity Testing Strategies

      • Susanne N. Kolle, Wera Teubner, Robert Landsiedel

      Pages 27-40

3. Environmental Threats to the Skin

   1. Front Matter

      Pages 41-41

      PDF

   2. Contact Allergy

      • Stefan F. Martin

      Pages 43-49

   3. Contact Urticaria and Contact Urticaria Syndrome

      • Hans F. Merk

      Pages 51-55

   4. Risk Assessment for Contact Allergens

      • David A. Basketter

      Pages 57-65

   5. UV and Skin: Photocarcinogenesis

      • Allen S. W. Oak, Mohammad Athar, Nabiha Yusuf, Craig A. Elmets

      Pages 67-103

   6. Ambient Particulate Matter and Skin

      • Andrea Vierkötter, Jean Krutmann, Tamara Schikowski

      Pages 105-111

   7. POPs and Skin

      • M. M. Leijs, Janna G. Koppe, T. Kraus, J. M. Baron, H. F. Merk

      Pages 113-130

​​This book is a rich source of information on skin disorders due to toxicants in the environment. State of the art knowledge is summarized concerning the molecular basis of skin damage caused by well-appreciated environmental noxae. The book also provides a uniquely comprehensive overview of the detrimental dermatological effects of exposure to air pollution and global climate change. A special focus is contact allergy, which, beyond representing a major problem in dermatotoxicology, serves as a prime example for the development of toxicological approaches to risk assessment. A further chapter is devoted to contact urticaria, a condition that can progress to life-threatening anaphylactic reactions. The novel information offered in this book will enable the reader to go beyond the traditional thinking of dermatotoxicology and achieve a modern appreciation of the highly complex interplay between skin and environment.

• Climate change
• Contact allergy
• Dermatotoxicology
• Risk assessment
• UV

• IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany

  Jean Krutmann

• Universitätsklinikum Aachen Klinik für Dermatologie u. Allergologie, Aachen, Germany

  Hans F. Merk

Jean Krutmann is Professor of Dermatology and Environmental Medicine and Director of the Institut für Umweltmedizinische Forschung (Institute for Environmental Medical Research) at the Heinrich Heine University, Düsseldorf. His field of research is dermatotoxicology and immunodermatology, with special emphasis on environmentally induced skin diseases. He is author or co-author of more than 200 papers and the recipient of various awards.

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