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Immunotherapy for Gastrointestinal Cancer

  • David Kerr
  • Rebecca Johnson

Table of contents

  1. Front Matter
    Pages i-viii
  2. Rachel Kerr
    Pages 1-22
  3. Vanessa Deschoolmeester, David Kerr, Patrick Pauwels, Jan B. Vermorken
    Pages 23-46
  4. Chris Heery, Anteneh Tesfaye, Benjamin Weinberg, John Marshall
    Pages 47-78
  5. Eirini Pectasides, David McDermott
    Pages 115-146
  6. Mark A. Glaire, David N. Church
    Pages 187-215
  7. Volker Heinemann, Sebastian Stintzing
    Pages 217-244
  8. Back Matter
    Pages 245-252

About this book

Introduction

This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy.

Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection.  The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed.  Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage.

Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists.  

Keywords

Cancer Immunotherapy Vaccine antibody cytokine tumor management

Editors and affiliations

  • David Kerr
    • 1
  • Rebecca Johnson
    • 2
  1. 1.Nuffield Division of Clinical and Laboratory SciencesUniversity of OxfordOxfordUnited Kingdom
  2. 2.John Radcliffe HospitalOxford University Hospitals NHS Trust John Radcliffe HospitalOxfordshireUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-43063-8
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-43061-4
  • Online ISBN 978-3-319-43063-8
  • Buy this book on publisher's site
Industry Sectors
Pharma
Health & Hospitals
Biotechnology