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  • © 2017

Bone Metastases from Prostate Cancer

Biology, Diagnosis and Management

Editors:

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  • Equips readers with an excellent understanding of metastasis formation and prognostic factors

  • Explains how best to achieve early diagnosis

  • Presents the latest evidence from the literature and clinical trials regarding treatment options and evaluation of response

  • Features a multidisciplinary approach, with contributions from a range of specialists

  • Includes supplementary material: sn.pub/extras

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  • ISBN: 978-3-319-42327-2
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Table of contents (21 chapters)

  1. Front Matter

    Pages i-x
  2. Bone Homing and Metastasis

    • Matteo Santoni, Antonio Lopez-Beltran, Marina Scarpelli, Roberta Mazzucchelli, Rossana Berardi, Liang Cheng et al.
    Pages 25-32
  3. Markers of Prostate Cancer: The Role of Circulating Tumor Markers in the Management of Bone Metastases

    • Massimo Gion, Chiara Trevisiol, Giulia Rainato, Aline S. C. Fabricio
    Pages 33-45
  4. Circulating Tumor Cells (CTCs) and Metastatic Prostate Cancer (mPCa)

    • Elisabetta Rossi, Rita Zamarchi
    Pages 47-59
  5. Imaging of Glycolysis with 18F-FDG PET

    • Hossein Jadvar, Laura Evangelista
    Pages 87-94
  6. New Radiopharmaceutical Markers for Metabolism and Receptor

    • Francesco Ceci, Joshua James Morigi, Lucia Zanoni, Stefano Fanti
    Pages 95-104
  7. Bone Metastases from Prostate Cancer: Hormonal Therapy

    • Elisa Zanardi, Carlo Cattrini, Francesco Boccardo
    Pages 105-120
  8. Chemotherapy

    • Giovanni Luca Ceresoli, Maria Bonomi, Maria Grazia Sauta
    Pages 121-133
  9. Combinations of Hormonal Therapy and Chemotherapy

    • Giovanni Luca Ceresoli, Maria Bonomi, Maria Grazia Sauta, Elisa Zanardi, Francesco Boccardo
    Pages 135-146
  10. Surgery: Treatment of Oligometastatic Disease

    • Alessandro Luzzati, Gennaro Scotto, Giuseppe Perrucchini, Carmine Zoccali
    Pages 147-161
  11. Bone Metastases from Prostate Cancer: Radiotherapy

    • Barbara Avuzzi, Riccardo Valdagni
    Pages 163-180
  12. Bone-Targeted Agents

    • Daniele Santini, Carla Ripamonti, Alice Zoccoli, Michele Iuliani, Marco Fioramonti, Giulia Ribelli et al.
    Pages 181-192
  13. Bone-Seeking Radionuclide for Therapy

    • Joe O’Sullivan, Phil Turner
    Pages 193-207
  14. New Frontiers in Treatment

    • Sergio Bracarda, Alketa Hamzaj, Kalliopi Andrikou
    Pages 209-221
  15. Approaches for Assessment of Response of Bone Metastases to Therapies

    • Emilio Bombardieri, Francesco Mungai, Maria Bonomi, Lucia Setti, Eugenio Borsatti, Gianluigi Ciocia et al.
    Pages 223-249
  16. Bone Metastases from Prostate Cancer: From Symptom Control to Pain Palliation

    • Augusto Caraceni, Ernesto Zecca, Fabio Formaglio, Francesca Ricchini
    Pages 251-270

About this book

This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.

Keywords

  • Bone-targeted agents
  • Markers of prostate cancer
  • Formation of bone metastases
  • Nuclear medicine techniques
  • Radiotherapy for bone metastases
  • Bone-seeking radionuclides
  • Circulating cells
  • Hormonal therapy
  • Combined hormonal therapy and chemotherapy
  • Radiaton Oncology

Reviews

“This is a very interesting book centered on bone metastases from prostate cancer, edited and authored by a multidisciplinary team with specific experience in the field. … The interest of the book increases because many new tools have recently been added to the diagnostic and therapeutic paraphernalia, giving hope also to patients surviving with a very bad quality of life and with a rapidly negative fate.” (Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 46, 2019)

Editors and Affiliations

  • University of Verona, Director of Metabolic Bone Diseases and Osteoncology Unit, Internal Medicine Department of Medicine, Verona, Italy

    Francesco Bertoldo

  • IRCCS AOU San Martino-IST National Cancer Research Institute, Department of Internal Medicine and Medical specialties (DIMI), School of Medical and Pharmacological Sciences, University of Genoa, Academic Unit of Medical Oncology, Department of Oncology (DIPOE), Genoa, Italy

    Francesco Boccardo

  • Humanitas Gavazzeni Clinic, Clical Scientific Director Department of Nuclear Medicine, Bergamo, Italy

    Emilio Bombardieri

  • Veneto Institute of Oncology IOV - IRCCS, Nuclear Medicine and Molecular imaging Unit, Padova, Italy

    Laura Evangelista

  • Radiation Oncology 1 and Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Department of Oncology and Hemato-oncology, Università di Milano, Milan, Italy

    Riccardo Valdagni

About the editors

Francesco Bertoldo, MD, is Associate Professor of Internal Medicine at the School of Medicine, University of Verona, Italy. Since 2003 he has been Chief of Bone and Mineral Metabolism Diseases and the Osteo-oncology Unit in the Department of Medicine, University Hospital GB Rossi, Verona, Italy. Dr. Bertoldo is a member of the Directive Council of the Italian Society of Osteoporosis and Bone Diseases (SIOMMMS) and of the Italian Society of Osteo-oncology. Since 2009 he has been a member of the Guidelines Committee of the Italian Association of Medical Oncology (AIOM) and SIOMMMS. In 2011 he served as coordinator of the Guidelines for Bone Disease in Prostate Cancer produced by the Italian Society of Urology. He has published more than 100 papers in national and international journals in the field of metabolic and cancer-related bone diseases.

Francesco Boccardo graduated cum laude in 1975 from the Medical School of the University of Genoa, Italy, where he then specialized in Oncology. He started his professional career in 1977 at the National Cancer Institute in Genoa and is now Director of the Academic Unit of Medical Oncology at the Institute. In 1998 he was appointed Full Professor of Medical Oncology at the Medical School of the University of Genoa, Italy, where, since 2001 he has been Director of the Postgraduate Medical School in Medical Oncology. Dr. Boccardo has served as President of the Italian Association of Medical Oncology (AIOM) and was one of the founders of the Italian Society of Urologic Oncology (SIURO).

Emilio Bombardieri, MD, is a specialist in Nuclear Medicine, Oncology, and Sports Medicine who is currently Clinical Scientific Director of Nuclear Medicine at the Humanitas Gavazzeni Hospital, Bergamo, Italy. In a long career he became Director of the Nuclear Medicine Division of the Istituto Nazionale Tumori, Milan in 1994 and Director of the Department of Diagnostic Imaging and Radiotherapy at the Institute in 2007. Since 1982 he has been Professor of Physiology and Endocrinology at the Catholic University, ISEF, Milan. Dr. Bombardieri has served as President of the Italian Association of Nuclear Medicine (AIMN), has chaired the EANM (European Association of Nuclear Medicine) Oncology Committee, and was nominated President of the EANM Congress 2012 in Milan. He has published more than 400 papers in national and international journals, and several scientific textbooks in Diagnostic Imaging and Oncology.

Laura Evangelista, MD, PhD, is a nuclear medicine physician at Veneto Institute of Oncology IOV – IRCCS, Padua, Italy. Following a residency in Nuclear Medicine at University “Federico II” of Napoli, Italy, she worked as a research fellow at the University “Federico II” of Napoli, the Memorial Sloan Kettering Hospital, New York City, and the Mayo Clinic of Rochester, USA, focusing on PET/CT in breast cancer, prostate cancer, and other oncological diseases. She is a member of the Translational and Molecular Imaging Committee for the European Association of Nuclear Medicine. She has published about 100 papers in national and international journals in the field of nuclear medicine.


Riccardo Valdagni has been Head of the Oncologic Radiotherapy Unit at the National Cancer Institute in Milan since 2011 and Head of the Prostate Program since 2003. Since 2009 he has been Vice President of the Italian Society of Oncologic Urology (SIUrO) and in 2010 he became a member of the Steering Committee of the multicenter international active surveillance protocol PRIAS (Prostate Cancer Research International: Active Surveillance). Dr. Valdagni is dedicated to the development of an integrated and multidisciplinary approach to prostate cancer. He has always been interested in psychology and psycho-oncology, and is a professor at the Il Ruolo Terapeutico psychoanalytic therapy center. He is the author of many international scientific publications in the field of Oncology. 


 

 

Bibliographic Information

  • Book Title: Bone Metastases from Prostate Cancer

  • Book Subtitle: Biology, Diagnosis and Management

  • Editors: Francesco Bertoldo, Francesco Boccardo, Emilio Bombardieri, Laura Evangelista, Riccardo Valdagni

  • DOI: https://doi.org/10.1007/978-3-319-42327-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-42326-5

  • Softcover ISBN: 978-3-319-82553-3

  • eBook ISBN: 978-3-319-42327-2

  • Edition Number: 1

  • Number of Pages: X, 293

  • Number of Illustrations: 23 b/w illustrations, 40 illustrations in colour

  • Topics: Oncology, Urology, Nuclear Medicine, Radiology, Orthopaedics, Pathology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

Buying options

eBook
USD 109.00
Price excludes VAT (USA)
  • ISBN: 978-3-319-42327-2
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 149.99
Price excludes VAT (USA)
Hardcover Book
USD 149.99
Price excludes VAT (USA)