Hepatocellular Carcinoma

Diagnosis and Treatment

  • Brian I. Carr

Part of the Current Clinical Oncology book series (CCO)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Causes, Biological and Molecular Bases of HCC

    1. Front Matter
      Pages 1-1
    2. Donna L. White, Fasiha Kanwal, Li Jiao, Hashem B. El-Serag
      Pages 3-24
    3. Hani Alotaibi, Nese Atabey, Kasım Diril, Esra Erdal, Mehmet Ozturk
      Pages 43-63
    4. Yvonne P. Dragan
      Pages 65-92
    5. Anuradha Budhu, Xin Wei Wang
      Pages 93-112
    6. Jean-Charles Nault, Jessica Zucman-Rossi
      Pages 113-119
    7. Aldo Cavallini
      Pages 121-137
    8. Nicolas Goossens, Ismail Labgaa, Augusto Villanueva
      Pages 139-147
    9. Sven H. Loosen, Christoph Roderburg, Tom Luedde
      Pages 149-155
    10. Antonio Mazzocca, Giovanni Ferraro, Giovanni Misciagna, Brian I. Carr
      Pages 157-161
    11. Brian I. Carr
      Pages 163-166
    12. Evgeny V. Denisov, Tatiana S. Gerashchenko, Marina V. Zavyalova, Vasiliy N. Manskikh, Evgeny L. Choinzonov, Nadezhda V. Cherdyntseva et al.
      Pages 211-228
    13. Inbal Houri, Oren Shibolet
      Pages 243-259
    14. Ryota Masuzaki, Tatsuo Kanda, Haruhiko Yoshida, Naoya Kato, Masao Omata
      Pages 261-273
    15. Chadia L. Robertson, Devanand Sarkar, Arun J. Sanyal
      Pages 275-286

About this book


Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC indidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists. 

"This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology

"...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease


gastroenterology hepatocellucal carcinoma oncology surgical oncology hepatology

Editors and affiliations

  • Brian I. Carr
    • 1
  1. 1.Dokuz Eylul UniversityIzmir Biomedicine and Genome Center Dokuz Eylul UniversityIzmirTurkey

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-34214-6
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-34212-2
  • Online ISBN 978-3-319-34214-6
  • About this book
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