Overview
- A complete overview of alternating electric fields therapy in clinical practice
- Covers the therapeutic application for a variety of malignancies
- Written for a broad audience that includes clinicians, biomedical engineers and mitosis researchers
- Includes supplementary material: sn.pub/extras
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo.
Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses thatwere performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies.
Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.
Editors and Affiliations
About the editor
Eric T. Wong, MD
Associate Professor of Neurology
Beth Israel Deaconess Medical Center
330 Brookline Avenue
Boston, MA 02215, USA
Bibliographic Information
Book Title: Alternating Electric Fields Therapy in Oncology
Book Subtitle: A Practical Guide to Clinical Applications of Tumor Treating Fields
Editors: Eric T. Wong
DOI: https://doi.org/10.1007/978-3-319-30576-9
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-30574-5Published: 02 November 2016
Softcover ISBN: 978-3-319-80840-6Published: 07 July 2018
eBook ISBN: 978-3-319-30576-9Published: 24 October 2016
Edition Number: 1
Number of Pages: XIV, 129
Number of Illustrations: 52 b/w illustrations
Topics: Oncology, Neurology, Neuroradiology
Industry Sectors: Biotechnology, Health & Hospitals, Pharma