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Growth Hormone Deficiency

Physiology and Clinical Management

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  • © 2016

Overview

  • Describes both the mechanism of human growth hormone (HGH) and the etiology, diagnosis and management of HGH deficiency

  • Discusses not only HGH but also its interaction with sex steroids, thyroid hormones and syndromes that cause or are associated with HGH deficiency

  • Covers diagnosis and management of both pediatric and adult HGH deficiency

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Table of contents (15 chapters)

  1. Mechanisms of Human Growth Hormone Secretion and Action

  2. Diagnosis of Human Growth Hormone Deficiency

  3. Etiologies of Human Growth Hormone Deficiency

Keywords

About this book

Providing the most current information on the function of human growth hormone (GH) and the consequences of its deficiency, this practical yet comprehensive text is divided into three sections. Part one describes the mechanisms of GH secretion and action, including the physiology of GH and its regulation by sex steroids and thyroid hormones, the effects of both under nutrition and obesity on GH secretion, and the metabolic effects of human recombinant GH therapy. The second section covers diagnostic strategies and tests for GH deficiency in both children and adults, including MRI of the pituitary. The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist.

Editors and Affiliations

  • Harvard Medical School , Boston Children's Hospital, Boston, USA

    Laurie E. Cohen

About the editor

Laurie E. Cohen, MD, Director of Clinical Operations, Division of Endocrinology, Director, Neuroendocrinology Program, Boston Children's Hospital, Boston, MA, USA

Bibliographic Information

  • Book Title: Growth Hormone Deficiency

  • Book Subtitle: Physiology and Clinical Management

  • Editors: Laurie E. Cohen

  • DOI: https://doi.org/10.1007/978-3-319-28038-7

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-28036-3Published: 19 July 2016

  • Softcover ISBN: 978-3-319-80261-9Published: 31 May 2018

  • eBook ISBN: 978-3-319-28038-7Published: 04 July 2016

  • Edition Number: 1

  • Number of Pages: XIII, 228

  • Number of Illustrations: 18 b/w illustrations, 10 illustrations in colour

  • Topics: Endocrinology, Metabolic Diseases

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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