Bioengineering and Cancer Stem Cell Concept

  • Mirjana Pavlovic
  • Bela Balint

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Mirjana Pavlovic, Bela Balint
    Pages 1-23
  3. Mirjana Pavlovic, Bela Balint
    Pages 43-56
  4. Mirjana Pavlovic, Bela Balint
    Pages 71-72
  5. Mirjana Pavlovic, Bela Balint
    Pages 73-87
  6. Mirjana Pavlovic, Bela Balint
    Pages 89-95
  7. Mirjana Pavlovic, Bela Balint
    Pages 97-102
  8. Mirjana Pavlovic, Bela Balint
    Pages 103-121
  9. Mirjana Pavlovic, Bela Balint
    Pages 123-131
  10. Mirjana Pavlovic, Bela Balint
    Pages 133-137
  11. Mirjana Pavlovic, Bela Balint
    Pages 139-144

About this book


This book explores the role of cancer stem cells in the diagnosis, treatment, and cure of cancers. This book also tackles novel methodology for cancer stem cell marker identification, cancer stem cell respiration and metabolism, genetic and epigenetic mechanisms including DNA methylation, and mi-RNA assemble. It also emphasizes the role of Bioinformatics techniques, which provide a novel methodology for modeling cancer outcomes.

The authors investigate the difference between cancer stem cells and normal stem cells, along with the concept of targeted cancer stem cell therapy. Although the theoretical explanations of cancer stem cell involvement in leukemia and solid cancers are controversial, there is now little doubt that cancer stem cells exist within otherwise heterogeneous cancer cell population. The brief examines the two leading theories, hierarchical and the stochastic/cancer stem cell model.

Researchers, professors and advanced-level students focused on bioengineering and computer science will find this book to be a valuable resource. It is a very good source of critical references for understanding of this problem, and a useful tool for professionals in related fields.


Bioengineering of tumors Bioinformatics Antitumor therapy Cancer stem cell Genetics Epigenetics Markers Respiration Metabolism Targeted cancer stem cell therapy

Authors and affiliations

  • Mirjana Pavlovic
    • 1
  • Bela Balint
    • 2
  1. 1.Department of Computer and Electrical Engineering and Computer ScienceFlorida Atlantic UniversityBoca RatonUSA
  2. 2.Institute for Hematology and TransfusiologyMilitary Medical AcademyBelgradeSerbia

Bibliographic information

  • DOI
  • Copyright Information The Author(s) 2015
  • Publisher Name Springer, Cham
  • eBook Packages Computer Science
  • Print ISBN 978-3-319-25668-9
  • Online ISBN 978-3-319-25670-2
  • About this book
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