About this book
Introduction
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
Keywords
Cold Ischemia Time Molecular Analysis Methods Preservation of Tissue Two-Temperature Fixation Vacuum-based Preservation
Editors and affiliations
- Manfred Dietel
- Christian Wittekind
- Gianni Bussolati
- Moritz von Winterfeld
- 1.Institute of PathologyCharité University MedicineBerlinGermany
- 2.Institute of PathologyUniversity Hospital LeipzigLeipzigGermany
- 3.University of Turin Institute of PathologyTurinItaly
- 4.Institute of PathologyCharité University MedicineBerlinGermany
Bibliographic information