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Complex Structure and Dynamics of the Heart

  • Philip Bittihn

Part of the Springer Theses book series (Springer Theses)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Philip Bittihn
    Pages 1-24
  3. Philip Bittihn
    Pages 25-84
  4. Philip Bittihn
    Pages 85-169
  5. Philip Bittihn
    Pages 171-185
  6. Back Matter
    Pages 187-204

About this book

Introduction

This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock – currently the only reliable way to terminate life-threatening fibrillation – by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.

Keywords

Cardiac Dynamics Electric-field-based Control Strategies Fibrillation and Defibrillation Heart Muscle as Excitable Medium Heart as a Complex System Mathematical Models of Cardiac Tissue Numerical Simulations of Heart Dynamics

Authors and affiliations

  • Philip Bittihn
    • 1
  1. 1.Research Group Biomedical PhysicsMax Planck Institute for Dynamics and Self-OrganizationGöttingenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-12232-8
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-3-319-12231-1
  • Online ISBN 978-3-319-12232-8
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • Buy this book on publisher's site
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