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Animal Cell Culture

  • Mohamed Al-Rubeai

Part of the Cell Engineering book series (CEEN, volume 9)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Hansjoerg Hauser
    Pages 1-25
  3. Volker Jäger, Konrad Büssow, Thomas Schirrmann
    Pages 27-64
  4. R. Pörtner
    Pages 89-135
  5. Jeffrey J. Chalmers, Ningning Ma
    Pages 169-183
  6. Sebastian Schwamb, Robert Puskeiler, Philipp Wiedemann
    Pages 185-221
  7. Michael Butler
    Pages 223-236
  8. Maureen Spearman, Michael Butler
    Pages 237-258
  9. Nishikant P. Shirsat, Niall J. English, Brian Glennon, Mohamed Al-Rubeai
    Pages 259-326
  10. Darrin Kuystermans, Mohamed Al-Rubeai
    Pages 327-372
  11. Véronique Chotteau
    Pages 407-443
  12. Stephan C. Kaiser, Matthias Kraume, Dieter Eibl, Regine Eibl
    Pages 445-500
  13. Laura A. Palomares, Mauricio Realpe, Octavio T. Ramírez
    Pages 501-519
  14. João V. Sá, Tiago M. Duarte, Manuel J. T. Carrondo, Paula M. Alves, Ana P. Teixeira
    Pages 521-539
  15. Ana Carina Silva, António Roldão, Ana Teixeira, Paulo Fernandes, Marcos F. Q. Sousa, Paula M. Alves
    Pages 541-563
  16. Eric Baek, Che Lin Kim, Jin Hyoung Park, Gyun Min Lee
    Pages 565-590
  17. Kelley Heffner, Christian Schroeder Kaas, Amit Kumar, Deniz Baycin-Hizal, Michael Betenbaugh
    Pages 591-614
  18. Miroslava Čuperlović-Culf
    Pages 615-646
  19. Philippe Herman, Katia Pauwels
    Pages 689-716
  20. Darrin Kuystermans, Mohamed Al-Rubeai
    Pages 717-757
  21. Back Matter
    Pages 759-763

About this book

Introduction

​Animal cells are the preferred “cell factories” for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve as a comprehensive review of animal cell culture, covering the current status of both research and applications. For the student or R&D scientist or new researcher the protocols are central to the performance of cell culture work, yet a broad understanding is essential for translation of laboratory findings into the industrial production. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field to produce state-of-the-art collection of current research. A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is a recommended volume for all biotechnology libraries.

Keywords

Animal Cell Culture Biologics Biopharmaceuticals Bioprocessing Therapeutic Products

Editors and affiliations

  • Mohamed Al-Rubeai
    • 1
  1. 1.University College DublinDublinIreland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-10320-4
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-10319-8
  • Online ISBN 978-3-319-10320-4
  • Series Print ISSN 1389-6946
  • Buy this book on publisher's site
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