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Transfusion in the Intensive Care Unit

  • Book
  • © 2015

Overview

Editors:
  1. Nicole P. Juffermans

    1. Department of Intensive Care L.E.I.C.A., Academic Medical Center, Amsterdam, The Netherlands

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  2. Timothy S. Walsh

    1. MRC Centre for Inflammation Research, University of Edinburgh The Queens Medical Research Institute, Edinburgh, United Kingdom

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    You can also search for this editor in PubMed   Google Scholar

  • Offers practical guidelines for transfusion tailored to specific ICU patient populations

  • Summarizes results from clinical trials performed in the past decade which have studied transfusion triggers for red blood cells, plasma, and platelets in the ICU

  • Provides background on the pathophysiology of anemia in the critically ill, the tolerance of specific patient groups to anemia and the purpose of red blood cell transfusion

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-vi
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  2. Introduction

    • Nicole P. Juffermans, Timothy S. Walsh
    Pages 1-4

  3. Causes of Anemia in Critically Ill Patients

    • Daniela Ortega, Yasser Sakr
    Pages 5-12

  4. Red Blood Cell Transfusion Trigger in Sepsis

    • Jean-Louis Vincent
    Pages 13-23

  5. Red Blood Cell Transfusion Trigger in Cardiac Disease

    • Parasuram Krishnamoorthy, Debabrata Mukherjee, Saurav Chatterjee
    Pages 25-34

  6. Red Blood Cell Transfusion Trigger in Cardiac Surgery

    • Gavin J. Murphy, Nishith N. Patel, Jonathan A. C. Sterne
    Pages 35-44

  7. Red Blood Cell Transfusion Trigger in Brain Injury

    • Shane W. English, Dean Fergusson, Lauralyn McIntyre
    Pages 45-58

  8. Red Blood Cell Transfusion in the Elderly

    • Matthew T. Czaja, Jeffrey L. Carson
    Pages 59-69

  9. ScvO2 as an Alternative Transfusion Trigger

    • Szilvia Kocsi, Krisztián Tánczos, Zsolt Molnár
    Pages 71-75

  10. Alternatives to Red Blood Cell Transfusion

    • Howard L. Corwin, Lena M. Napolitano
    Pages 77-91

  11. Blood-Sparing Strategies in the Intensive Care Unit

    • Andrew Retter, Duncan Wyncoll
    Pages 93-100

  12. Massive Transfusion in Trauma

    • Daniel Frith, Karim Brohi
    Pages 101-119

  13. Transfusion in Gastrointestinal Bleeding

    • Vipul Jairath
    Pages 121-137

  14. Platelet Transfusion Trigger in the Intensive Care Unit

    • D. Garry, S. Mckechnie, S. J. Stanworth
    Pages 139-149

  15. FFP Transfusion in Intensive Care Medicine

    • David Hall, Timothy S. Walsh
    Pages 151-159

  16. Transfusion-Related Acute Lung Injury

    • Alexander P. J. Vlaar, Nicole P. Juffermans
    Pages 161-169

  17. Transfusion-Associated Circulatory Overload

    • Leanne Clifford, Daryl J. Kor
    Pages 171-182

  18. Back Matter

    Pages 183-187
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Keywords

About this book

Due to a high incidence of anemia, critically ill patients are frequently transfused, with up to 40% of patients receiving a transfusion during their stay in the Intensive Care Unit. It has become increasingly clear that there is an association between transfusion and adverse outcomes, underlining the need for a careful assessment of the risks and benefits of a blood transfusion. In the last decade, there have been several large clinical trials that have studied red blood cell transfusion triggers in various ICU patient populations, allowing us to take a personalized approach to transfusion. Moreover, ICU patients often suffer from coagulopathy. Recent studies have addressed the effectiveness of fresh frozen plasma and platelets to prevent or treat bleeding. Aiming at a personalized therapy approach in transfusion practice, this book is the first to offer a comprehensive summary of transfusion triggers for red blood cells in specific ICU patient populations and specific conditions. In addition, it discusses evidence for triggers for plasma and platelets and outlines the most common adverse effects of transfusion in the ICU. Transfusion in the Intensive Care Unit is a practical handbook that can be used in everyday practice to guide transfusion and thus will serve as a valuable resource for physicians, fellows and residents working in Intensive Care, Anesthesiology and Cardiac Surgery.

Reviews

From the book reviews:

“This book reviews transfusion thresholds and data surrounding the use of blood products in various populations of critically ill patients. … With its easy-to-read style, this book is appropriate for practitioners at all levels and disciplines working in the critical care unit. Trauma practitioners, neurosurgeons, and cardiothoracic specialists also may benefit from these focused reviews. … This is a timely review of a rapidly evolving field.” (David J. Dries, Doody’s Book Reviews, January, 2015)

Editors and Affiliations

  • Department of Intensive Care L.E.I.C.A., Academic Medical Center, Amsterdam, The Netherlands

    Nicole P. Juffermans

  • MRC Centre for Inflammation Research, University of Edinburgh The Queens Medical Research Institute, Edinburgh, United Kingdom

    Timothy S. Walsh

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