Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells

  • Julia Köritzer

Part of the Springer Theses book series (Springer Theses)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Julia Köritzer
    Pages 1-18
  3. Julia Köritzer
    Pages 19-34
  4. Julia Köritzer
    Pages 35-46
  5. Julia Köritzer
    Pages 47-49
  6. Back Matter
    Pages 51-74

About this book

Introduction

Cold atmospheric plasma is an auspicious new candidate in cancer treatment. Cold atmospheric plasma (CAP) is a partially ionized gas in which the ion temperature is close to room temperature. It contains electrons, charged particles, radicals, various excited molecules and UV photons. These various compositional elements have the potential to inhibit cancer cell activity whilst doing no harm to healthy cells. Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults; treatment including surgery, radio- and chemotherapy remains palliative for most patients as a cure remains elusive. The successful combination of the standard chemotherapeutic temozolomide (TMZ) and CAP treatment features synergistic effects even in resistant glioma cells. In particular in glioma therapy, CAP could offer an innovative approach allowing specific cancer cell / tumor tissue inhibition without damaging healthy cells. Thus CAP is a promising candidate for combination therapy especially for patients suffering from GBMs showing TMZ resistance.

Keywords

Brain Tumor Chemotherapeutic Temozolomide Cold Atmospheric Plasma Glioblastoma Multiforme Glioblastoma Treatment O6-methylguanine–DNA Methyltransferase Plasma Medicine Plasma in Cancer Treatment Reactive Oxygen Species

Authors and affiliations

  • Julia Köritzer
    • 1
  1. 1.Max Planck Institute for Extraterrestrial PhysicsGarchingGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-06224-2
  • Copyright Information Springer International Publishing Switzerland 2014
  • Publisher Name Springer, Cham
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-3-319-06223-5
  • Online ISBN 978-3-319-06224-2
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • About this book
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