Inflammation and Oxidative Stress in Neurological Disorders

Effect of Lifestyle, Genes, and Age

  • Akhlaq A. Farooqui

About this book


Consumption of healthy balanced diet (colored and green vegetables, fresh fruits, lean meats, fish, and whole grain) along with moderate exercise (30-45 min/day), and 6-7 hours of sleep results in a healthier blood pressure pattern and low cholesterol levels leading into a reduced risk of obesity related diseases, such as diabetes, and metabolic syndrome. Both these pathological conditions are not only the risk factors for heart disease, but also contribute and promote the risk for stroke, Alzheimer disease, and depression. A healthy lifestyle -- which includes a healthy diet with plenty of fruits and vegetables, moderate exercise for maintaining a healthy body weight, and optimal sleep may help in preventing not only diabetes, and metabolic syndrome, but delaying the pathogenesis of stroke, Alzheimer disease, and depression. Information on diet, exercise, and sleep is scattered throughout the literature in the form of original papers, reviews, and some books, which deal with the effects of diet, exercise, and sleep on viscera. This monograph is the first to describe the effect of neuroinflammation and oxidative stress in relation to diet, exercise, and sleep on brain. It describes the contribution of dietary carbohydrates, fats, protein, and nucleic acids in neuroinflammation and oxidative stress in the normal aged brain and in the brains of patients with neurological disorders.  

Inflammation and Oxidative Stress in the Brain presents readers with cutting edge and comprehensive information on the effect of diet, exercise, and sleep on neuroinflammation and oxidative stress in normal brains and brains from patients with neurological disorders. It is hoped that this monograph will be useful to postgraduate students, faculty, research scientists, nutritionists, exercise physiologists, and physicians, who are curious about the molecular mechanisms that link neuroinflammation and oxidative stress with the pathogenesis of neurotraumatic, neurodegenerative, and neuropsychiatric disorders.


Neuroinflammation anti-inflammatory metabolites antioxidant systems cytokines hemokines proinflammatory metabolites

Authors and affiliations

  • Akhlaq A. Farooqui
    • 1
  1. 1.ColumbusUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2014
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-04110-0
  • Online ISBN 978-3-319-04111-7
  • About this book
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