Progress in Neuropeptide Research

1. Front Matter

   Pages I-VIII

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2. Neuropeptides and immune response

   1. Front Matter

      Pages 1-1

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   2. Somatostatin — An Antiproliferative Hormone?

      • Marek Pawlikowski, Jolanta Kunert-Radek, Henryk Stepien

      Pages 3-12

   3. Physiopathology of Circulating Immunoreactive Somatostatin in Man

      • S. M. Webb, J. Monés, J. Binimelis, M. A. Peinado

      Pages 13-17

   4. Nerves, Neuropeptides and Mucosal Immune Response

      • Andrzej M. Stanisz, Kenneth Croitoru, Peter Ernst, Ron Stead, John Bienenstock

      Pages 19-24

   5. Neuropeptides and Natural Killer Cell Activity

      • H. Stepien, P. Zelazowski, K. D. Döhler, M. Pawlikowski

      Pages 25-31

3. Pineal — neuroendocrine interaction

   1. Front Matter

      Pages 33-33

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   2. The Pineal Gland — An Integral Part of the Neuroendocrine System

      • M. Karasek

      Pages 35-43

   3. Relationship between Pineal Gland and Opioid System in Cancer Patients

      • F. Fraschini, D. Esposti, G. Esposti, V. Lucini, P. Lissoni, F. Scaglione et al.

      Pages 45-52

4. Neuropeptides in brain and peripheral tissues

   1. Front Matter

      Pages 53-53

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   2. Neuropeptides and Thyroid Function and Growth I. Sympathetic and Parasympathetic Intrathyroidal Nerves and Coexisting Peptides (NPY, VIP)

      • A. Lewinski

      Pages 55-63

   3. Neuropeptides and Thyroid Function and Growth II. Intrathyroidal Peptidergic Nerves and Neuropeptides Located in Parafollicular (C) Cells

      • A. Lewinski

      Pages 65-72

   4. The Expression of Neurohypophyseal Peptide Genes in Mammalian Gonadal Tissues

      • Richard Ivell, Craig A. McArdle

      Pages 73-81

   5. Possible Function of Testicular Opioid Peptides in the Control of Testicular Function

      • I. Gerendai

      Pages 83-90

   6. Circulating Vasopressin Attenuates the Increased Activity of the Sympathetic Nervous System Induced by Anterolateral Deafferentation of the Hypothalamus

      • B. Lichardus, R. Kvetnansky, G. Makara, Z. Oprsalová, N. Michajlovskij, O. Földes et al.

      Pages 91-97

   7. Distribution and Kinetics of 11C-Labelled Substance P, Met-Enkephalin and Related Peptides in the Head of the Rhesus Monkey

      • P. O. Lundberg, P. Hartvig, H. Lundqvist, B. Långström, C. Muhr, K. Någren et al.

      Pages 99-107

5. Ontogenetic development and brain organization

   1. Front Matter

      Pages 109-109

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   2. Marihuana and Pregnancy

      • T. Wenger, D. Croix, G. Tramu

      Pages 111-119

   3. Insulin-Dependent Brain Organization and Diabetes Mellitus

      • G. Dörner, A. Plagemann, J. Rückert, F. Götz, W. Rohde, F. Stahl et al.

      Pages 121-132

   4. The Ontogeny of Opioid Peptides and Their Action on LH Secretion in the Pig

      • N. Parvizi

      Pages 133-142

As early as in the twenties and thirties of our century Ernst Scharrer published papers suggesting, on the basis of morphological findings, that the brain exhibits secretory function which he called neurosecretion. Only a few decades later Scharrer's presumption was fully confirmed by the isolation of a number of neuropeptides and by the disclosure of their chemical stuctures. Neuropeptide research is one of the most rapidly expanding fields in biomedicin. Initially investigators focused their attention on the existence and role of neuropeptides within the hypothalamo-hypophyseal system. This particular area of research still provides plenty of interesting and fruitful findings. Neuropeptides -including those which were discovered as "hypothalamic" hormones­ can also be detected in other parts of the brain and even in peripheral organs. In fact, several neuropeptides were found to be synthesized not only by neurones but also by non-neuronal cells. These observations imply much wider functional relevance of neuropeptides than it had been supposed initially. It appears from present day knowledge, that neuropeptides are not only involved in neurotransmission and in the control of pituitary function but also in direct regulation of numerous peripheral biological processes, including reproduction, digestion, immune functions, and even cell growth. This volume includes the invited papers of the Symposium on "Progress in Neuropeptide Research" wh ich was held in Looz/Poland on September 8-10,1988. Topics ofthe symposium reflect upon newly discovered peptides, new localizations, new functions, and new technical approaches.

• biological
• brain
• cell
• cell growth
• cells
• fields
• growth
• isolation
• morphology
• paper
• peptide
• regulation
• reproduction
• system

• Institute of Endocrinology, Medical Academy of Lódź, Lódź, Poland

  M. Pawlikowski

• Bissendorf Peptide GmbH, Wedemark 2, Federal Republik of Germany

  K.-D. Döhler

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