Overview
- Updated information on synthesis methods for O-, C- and N-glycosides
- Presents novel approaches for determining absolute configuration
- Mechanistic insights
Access this book
Tax calculation will be finalised at checkout
Other ways to access
About this book
This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology. Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates.
Also, additional mechanistic evidence is presented for better understanding of the glycosylation reaction, trying to identify the variables mainly depending on protecting and leaving groups, as well as catalyst and reaction condition which altogether directs the anomeric stereo control.
A chapter on the glycoside hydrolysis is included in view ofthe increasing interest in the use of biomass as a natural and renewable source for obtaining important intermediates or products used in food or valuable materials.The author includes information in the characterization of glycosides section with the aim of giving additional tools for the structural assignment through NMR, X-Ray and mass spectra techniques.
Similar content being viewed by others
Keywords
Table of contents (10 chapters)
-
Front Matter
-
Back Matter
Authors and Affiliations
About the author
Marco Brito-Arias is at the National Polytechnic Institute in Mexico.
Bibliographic Information
Book Title: Synthesis and Characterization of Glycosides
Authors: Marco Brito-Arias
DOI: https://doi.org/10.1007/978-3-030-97854-9
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-030-97853-2Published: 23 April 2022
Softcover ISBN: 978-3-030-97856-3Published: 23 April 2023
eBook ISBN: 978-3-030-97854-9Published: 22 April 2022
Edition Number: 3
Number of Pages: XVII, 530
Number of Illustrations: 498 b/w illustrations, 201 illustrations in colour
Topics: Carbohydrate Chemistry, Biotechnology, Industrial Chemistry/Chemical Engineering, Medicinal Chemistry, Analytical Chemistry
Industry Sectors: Biotechnology, Chemical Manufacturing, Consumer Packaged Goods, Pharma