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  • Textbook
  • © 2020

Tissue-Specific Cell Signaling

  • First textbook to cover cell-specific signaling of over 20 cell-types by experts in the field

  • Covers topics from ligand/receptor interaction to organ/organism response

  • Tabular and well-illustrated, will be extremely valuable in the understanding of this complex field

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eBook USD 109.00
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  • ISBN: 978-3-030-44436-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
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  • Tax calculation will be finalised during checkout
Hardcover Book USD 149.99
Price excludes VAT (USA)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xviii
  2. Beyond Brain Signaling

    • Cátia D. Pereira, Filipa Martins, Fernanda Marques, João Carlos Sousa, Sandra Rebelo
    Pages 1-32
  3. Cell Signalling Within Pituitary, the Master Gland of the Endocrine System

    • Sofia S. Pereira, Carolina B. Lobato, Mariana P. Monteiro
    Pages 33-61
  4. Cell Signaling Within Endocrine Glands: Thyroid, Parathyroids and Adrenal Glands

    • Sofia S. Pereira, Carolina B. Lobato, Mariana P. Monteiro
    Pages 63-91Open Access
  5. Signaling Pathways Governing Activation of Innate Immune Cells

    • Bruno M. Neves, Catarina R. Almeida
    Pages 93-131
  6. Cell Activation and Signaling in Lymphocytes

    • Alexandre M. Carmo, Sónia N. Henriques
    Pages 133-161
  7. More Than Androgens: Hormonal and Paracrine Signaling in Prostate Development and Homeostasis

    • Juliana Felgueiras, Vânia Camilo, Margarida Fardilha, Carmen Jerónimo
    Pages 195-223
  8. Testicular Signaling: Team Work in Sperm Production

    • Joana Santiago, Daniela Patrício, Joana Vieira Silva
    Pages 225-255
  9. Sperm Signaling Specificity: From Sperm Maturation to Oocyte Recognition

    • Maria João Freitas, Daniela Patrício, Margarida Fardilha
    Pages 257-277
  10. Hormone Signaling Pathways in the Postnatal Mammary Gland

    • Fátima L. Monteiro, Inês Direito, Luisa A. Helguero
    Pages 279-315
  11. Oogenesis Signaling from Development to Environmental Plasticity and Aging

    • Bruno Marques, Ricardo Matos, Rui Gonçalo Martinho
    Pages 317-335
  12. Key Signaling Pathways in the Cardiovascular System

    • Fábio Trindade, Inês Falcão-Pires, Andreas Kavazis, Adelino Leite-Moreira, Daniel Moreira-Gonçalves, Rita Nogueira-Ferreira
    Pages 337-368
  13. Growth Factor Signaling in the Maintenance of Adult Lung Homeostasis

    • Henrique Araújo-Silva, Jorge Correia-Pinto, Rute S. Moura
    Pages 369-381
  14. The Signaling Pathways Involved in the Regulation of Skeletal Muscle Plasticity

    • Alexandra Moreira-Pais, Francisco Amado, Rui Vitorino, Hans-Joachim Appell Coriolano, José Alberto Duarte, Rita Ferreira
    Pages 383-408
  15. Adipocyte Specific Signaling

    • David F. Carrageta, Pedro F. Oliveira, Mariana P. Monteiro, Marco G. Alves
    Pages 409-436Open Access

About this book

Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters.

This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors.

Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Keywords

  • cell signaling
  • signal transduction
  • signal specificity
  • tissue regulation
  • proteome
  • tissue specificity

Editors and Affiliations

  • Laboratory of Signal Transduction, Department of Medical Sciences, Institute of Biomedicine—iBiMED, University of Aveiro, Aveiro, Portugal

    Joana Vieira Silva

  • Laboratory of Protein Phosphorylation and Proteomics, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Leuven, Belgium

    Maria João Freitas

  • Laboratory of Signal Transduction, Department of Medical Sciences, Institute of Biomedicine—iBiMED, University of Aveiro, Aveiro, Portugal

    Margarida Fardilha

About the editors

Joana Vieira Silva; Laboratory of Signal Transduction, Department of Medical Sciences, Institute of Biomedicine – iBiMED, University of Aveiro, Portugal; Institute for Innovation and Health Research (i3S), University of Porto, Portugal; Department of Microscopy, Laboratory of Cell Biology, and Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, Portugal; joanavieirasilva@ua.pt

Maria João Freitas; Laboratory of Protein Phosphorylation and Proteomics, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Leuven, Belgium; mariajoao.freitas@kuleuven.be

Margarida Fardilha; Laboratory of Signal Transduction, Institute for research in Biomedicine- iBiMED, Medical Sciences Department, University of Aveiro, Aveiro, Portugal; mfardilha@ua.pt

Bibliographic Information

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • ISBN: 978-3-030-44436-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book USD 149.99
Price excludes VAT (USA)