© 2020

Hormonal Pathology of the Uterus

  • Liane Deligdisch-Schor
  • Angelica Mareş Miceli
  • The permanently changing nature of hormone therapy with new pharmaceutical products and especially, new and challenging concepts on applying them will be addressed

  • The book will include clinical and pathological descriptions, theoretical and practical medical issues with important impact on women's health

  • The book will include both oncologic and fertility aspects of gynecological pathology


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1242)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Liane Deligdisch-Schor, Angelica Mareş Miceli
    Pages 1-12
  3. Pouya Javadian, Farr Nezhat
    Pages 59-72
  4. Tanja Pejovic, Sarah Thisted, Michael White, Farr R. Nezhat
    Pages 73-87
  5. John Paciuc
    Pages 89-120
  6. Liane Deligdisch-Schor
    Pages 145-177
  7. Back Matter
    Pages 179-185

About this book


Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women.  Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses.

This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health. 


hormonal effects on the uterus endometrial hyperplasia endometrial neoplasia myometrial benign tumors hormone therapy

Editors and affiliations

  • Liane Deligdisch-Schor
    • 1
  • Angelica Mareş Miceli
    • 2
  1. 1.Professor Emeritus, Department of Pathology, Department of Obstetrics-Gynecology and Reproductive ScienceIcahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.New York Medical CollegeWestchester Medical CenterValhallaUSA

About the editors

Dr. Liane Deligdisch-Schor graduated from Medical School in Bucarest, Romania, trained in Obstetrics-Gynecology and Pathology in Romania, then specializing in Gynecologic Pathology at the Magee Womens Hospital in Pittsburgh, Pa. and at the Free Hospital for Women, Harvard Medical School, Boston Mass. She founded the Division of Gynecologic Pathology and the course of Gynecologic Pathology at the Mount Sinai School of Medicine in New York where she is a tenured Professor since 1986 and Professor Emeritus since 2016, devoting her time to diagnosis, teaching and research activities. She was elected a member of the French National Academy of Medicine in 2007; authored over 150 peer reviewed articles and edited 7 textbooks, with the main topics early detection of neoplasms of the female genital tract and Hormonal Pathology of the Uterus. In addition to numerous case reports her publications include extensive studies of Ovarian Cancer precursors, with Histopathologic changes correlated to Computerized Image Analysis and Molecular Studies, being the first in the medical literature to describe Ovarian Dysplasia.  Numerous clinical-histopathologic studies of hormonal Pathology of the Uterus included ultrastructural and morphometric changes and viral DNA studies correlated to clinical aspects of Endometrial neoplastic lesions. Dr. Liane Deligdisch-Schor received numerous awards for teaching and research and is often invited as keynote speaker at national and international meetings. She is also an enthusiastic art lover and traveler.

Dr. Angelica Mareş Miceli graduated from Medical School in Bucharest, Romania, trained in Pathology in Bucharest and New York, then specialized in Gynecologic Pathology and Cytopathology at Mount Sinai Hospital in New York, under the mentorship of Dr Liane Deligdisch-Schor. Their research collaboration started more than fifteen years ago. Presently, Dr Mareş Miceli works in the field of Gynecologic Pathology and teaching in Pathology/ Pathophysiology Program at New York Medical College – School of Medicine. Her work includes diagnosis, clinical-pathologic correlation, teaching students and pathology residents, research on ovarian dysplasia and carcinoid ovarian tumors, and publishing; her interests are early diagnosis and the study of cancer precursors in gynecologic neoplasms, pediatric, adolescent and young adult gynecology. Dr. Mareş Miceli is involved in many academic activities, being a member in numerous committees for education and curriculum, promotions and career advisor; she received many awards for teaching and is often invited as speaker at national and international meetings. She is also an enthusiastic nature and art lover.

Bibliographic information

  • Book Title Hormonal Pathology of the Uterus
  • Editors Liane Deligdisch-Schor
    Angelica Mareş Miceli
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-030-38473-9
  • Softcover ISBN 978-3-030-38476-0
  • eBook ISBN 978-3-030-38474-6
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages VIII, 185
  • Number of Illustrations 7 b/w illustrations, 59 illustrations in colour
  • Topics Cancer Research
  • Buy this book on publisher's site
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