Skip to main content
SpringerLink
Log in
Book cover

Genomic Medicine

A Practical Guide

  • Book
  • © 2020

Overview

Editors:
  1. Laura J. Tafe

    1. Dartmouth–Hitchcock Medical Center, Lebanon, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Maria E. Arcila

    1. Memorial Sloan Kettering Cancer Center, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Provides a user-friendly, succinct reference

  • Synthesizes important major updates and guidelines in this field

  • Written by experts in the field

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. General Concepts

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Pre-analytics, Current Testing Technologies, and Limitations of Testing

      • Alejandro Luiña Contreras, Jose Jasper L. Andal, Raymundo M. Lo, Daphne C. Ang
      Pages 3-23

    3. Next-Generation Sequencing

      • Alanna J. Church
      Pages 25-40

    4. Cell-Free DNA Testing

      • Brennan Decker, Lynette M. Sholl
      Pages 41-54

    5. Role of Bioinformatics in Molecular Medicine

      • Chad Vanderbilt, Sumit Middha
      Pages 55-68

    6. Interpreting Genomic Reports

      • Alejandro Luiña Contreras
      Pages 69-80

  3. Applications in Solid Tumors

    1. Front Matter

      Pages 81-81
      Download chapter PDF

    2. Lung Carcinoma

      • Maria E. Arcila, Jason C. Chang, Laura J. Tafe
      Pages 83-101

    3. GI Including GIST

      • Efsevia Vakiani
      Pages 103-122

    4. Breast

      • Dara S. Ross
      Pages 123-131

    5. Genitourinary Tumors

      • Marie-Lisa Eich, George J. Netto
      Pages 133-147

    6. Gynecologic Malignancies

      • Jessica L. Dillon, Laura J. Tafe
      Pages 149-158

    7. Sarcomas

      • Konstantinos Linos
      Pages 159-182

    8. Salivary Gland Carcinomas

      • Snjezana Dogan
      Pages 183-195

    9. Sinonasal Carcinomas

      • Snjezana Dogan
      Pages 197-203

  4. Applications in Hematopathology

    1. Front Matter

      Pages 205-205
      Download chapter PDF

    2. Acute Myeloid Neoplasms

      • Eric Y. Loo
      Pages 207-233

    3. Chronic Myeloid Neoplasms

      • Maria E. Arcila, Caleb Ho
      Pages 235-251

    4. Lymphomas

      • Vignesh Shanmugam, Annette S. Kim
      Pages 253-315
Back to top

Keywords

About this book

The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care.


This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.

Editors and Affiliations

  • Dartmouth–Hitchcock Medical Center, Lebanon, USA

    Laura J. Tafe

  • Memorial Sloan Kettering Cancer Center, New York, USA

    Maria E. Arcila

About the editors

Laura J. Tafe, MD
Associate Professor of Pathology and Laboratory Medicine
Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
603-650-7211




Maria E. Arcila, MD
Associate attending Department of Pathology – Hematopathology and Molecular Diagnostics Services 
Memorial Sloan Kettering Cancer Center 
1275 York Ave
New York, NY 10065
212 6397879



Bibliographic Information

  • Book Title: Genomic Medicine

  • Book Subtitle: A Practical Guide

  • Editors: Laura J. Tafe, Maria E. Arcila

  • DOI: https://doi.org/10.1007/978-3-030-22922-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-22921-4Published: 16 October 2019

  • eBook ISBN: 978-3-030-22922-1Published: 26 September 2019

  • Edition Number: 1

  • Number of Pages: X, 325

  • Number of Illustrations: 1 b/w illustrations, 20 illustrations in colour

  • Topics: Pathology

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

Publish with us

Policies and ethics

Back to top

Search

Navigation