Table of contents

  1. Front Matter
    Pages i-xx
  2. Breaking the Diffraction Barrier in Fluorescence Microscopy

    1. Front Matter
      Pages 1-1
    2. Steffen J. Sahl, Stefan W. Hell
      Pages 3-32 Open Access
  3. Retinal Imaging and Image Guided Retina Treatment

    1. Front Matter
      Pages 33-33
    2. Jörg Fischer, Tilman Otto, François Delori, Lucia Pace, Giovanni Staurenghi
      Pages 35-57 Open Access
    3. Silke Aumann, Sabine Donner, Jörg Fischer, Frank Müller
      Pages 59-85 Open Access
    4. Philipp L. Müller, Sebastian Wolf, Rosa Dolz-Marco, Ali Tafreshi, Steffen Schmitz-Valckenberg, Frank G. Holz
      Pages 87-106 Open Access
    5. Robert N. Weinreb, Christopher Bowd, Sasan Moghimi, Ali Tafreshi, Sebastian Rausch, Linda M. Zangwill
      Pages 107-134 Open Access
    6. Roland Rocholz, Federico Corvi, Julian Weichsel, Stefan Schmidt, Giovanni Staurenghi
      Pages 135-160 Open Access
    7. Boy Braaf, Maximilian G. O. Gräfe, Néstor Uribe-Patarroyo, Brett E. Bouma, Benjamin J. Vakoc, Johannes F. de Boer et al.
      Pages 161-179 Open Access
    8. Dierck Hillmann, Clara Pfäffle, Hendrik Spahr, Helge Sudkamp, Gesa Franke, Gereon Hüttmann
      Pages 181-194 Open Access
    9. Tschackad Kamali, Spring RM. Farrell, William H. Baldridge, Jörg Fischer, Balwantray C. Chauhan
      Pages 195-211 Open Access
    10. Paul Bernstein, Chantal Dysli, Jörg Fischer, Martin Hammer, Yoshihiko Katayama, Lydia Sauer et al.
      Pages 213-235 Open Access
    11. Boris Považay, Ralf Brinkmann, Markus Stoller, Ralf Kessler
      Pages 237-259 Open Access
  4. Anterior Segment Imaging and Image Guided Treatment

    1. Front Matter
      Pages 261-261
    2. Oliver Stachs, Rudolf F. Guthoff, Silke Aumann
      Pages 263-284 Open Access
    3. Jacqueline Sousa Asam, Melanie Polzer, Ali Tafreshi, Nino Hirnschall, Oliver Findl
      Pages 285-299 Open Access
    4. Hui Sun, Andreas Fritz, Gerit Dröge, Tobias Neuhann, Josef F. Bille
      Pages 301-317 Open Access
  5. Adaptive Optics in Vision Science and Ophthalmology

    1. Front Matter
      Pages 337-337
    2. Gopal Swamy Jayabalan, Josef F. Bille
      Pages 339-358 Open Access
    3. Wolf M. Harmening, Lawrence C. Sincich
      Pages 359-375 Open Access
    4. Gopal Swamy Jayabalan, Ralf Kessler, Jörg Fischer, Josef F. Bille
      Pages 377-394 Open Access
  6. Back Matter
    Pages 395-407

About this book


This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. 

High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background.

Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.


Fluorescence Microscopy Ophthalmoscopy Optical Coherence Tomography Ultrafast Laser Surgery Retinal Imaging Adaptive optics Open access

Editors and affiliations

  • Josef F. Bille
    • 1
  1. 1.University HeidelbergHeidelbergGermany

Bibliographic information

  • DOI
  • Copyright Information The Editor(s) (if applicable) and The Author(s) 2019
  • License CC BY
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-030-16637-3
  • Online ISBN 978-3-030-16638-0
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals