Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient

1. Front Matter

   Pages i-xii

   PDF

2. Predisposing Diseases and Specific Considerations in Critical Illness

   1. Front Matter

      Pages 1-1

      PDF

   2. The Changing Landscape of the Critical Care of Pediatric Immunocompromised Hematology and Oncology Patients

      • Christine N. Duncan

      Pages 3-7

   3. Diagnosis and Treatment-Related Complications of Acute Leukemia

      • Lauren Pommert, Steven Margossian, Michael Burke

      Pages 9-28

   4. Neuro-oncologic Emergencies

      • Jessica Clymer, Peter E. Manley

      Pages 29-40

   5. Solid Tumors Outside of the Central Nervous System

      • Hilary C. Schreiber, James S. Killinger

      Pages 41-54

   6. Primary Immunodeficiency Diseases

      • Fayhan Alroqi, Abdulrahman Alsultan, Mohammed Essa

      Pages 55-70

   7. Care of the Critically Ill Pediatric Sickle Cell Patient

      • Tolulope Rosanwo, Jennifer A. McArthur, Natasha Archer

      Pages 71-93

   8. Bone Marrow Failure

      • Sajad Khazal, Jorge Ricardo Galvez Silva, Monica Thakar, David Margolis

      Pages 95-107

   9. Hematopoietic Stem Cell Transplant and Cellular Therapy

      • Priti Tewari, Rajinder Bajwa, Agne Taraseviciute, Jerelyn Moffet, David McCall, Kris M. Mahadeo

      Pages 109-158

   10. Diagnosis, Treatment, and Management of Hemophagocytic Lymphohistiocytosis in the Critical Care Unit

       • Melissa Hines, Neel Bhatt, Julie-An M. Talano

       Pages 159-182

3. Critical Care Management

   1. Front Matter

      Pages 183-183

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   2. Early Recognition of Critical Illness

      • Asya Agulnik

      Pages 185-194

   3. Acute Respiratory Failure and Management

      • Prakadeshwari Rajapreyar, Whitney Kopp, Adrienne Randolph

      Pages 195-210

   4. Cardiac Dysfunction in Hematology Oncology and Hematopoietic Cell Transplant Patients

      • Saad Ghafoor, Marshay James, Jason Goldberg, Jennifer A. McArthur

      Pages 211-235

   5. Acute Kidney Injury and Renal Replacement Therapy in Immunocompromised Children

      • Joseph Angelo, Ayse A. Arikan

      Pages 237-252

   6. Critical Care Management: Sepsis and Disseminated and Local Infections

      • Caitlin Hurley, Matt Zinter

      Pages 253-274

   7. ECMO Use in the Pediatric Immunocompromised Hematology/Oncology Patient

      • Robert A. Niebler, Leslie E. Lehmann

      Pages 275-290

   8. Pharmacy Implications

      • Stacey Albuquerque

      Pages 291-299

   9. Psychosocial and Palliative Care

      • Sarah Tarquini, Candice Chow, Christina Ullrich

      Pages 301-324

This volume provides a comprehensive overview of critical care of the pediatric immunocompromised hematology-oncology patient. The text focuses on unique aspects of the pediatric immunocompromised patient that predisposes the child to significant illness, and presents critical care management strategies specific to the patient population. In addition to chapters on oncology, primary immune deficiency, immunocompromised hematology, and hematopoietic cell transplant patients, the book covers the changing landscape of ICU care, pharmacologic considerations, and psychological and social aspects of the critical care of hematology-oncology patients.


Written by experts from a range of disciplines, Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide is a valuable resource for clinicians and practitioners who treat this patient population.

• leukemia
• sickle cell disease
• hematopoietic cell transplant
• sepsis
• post-traumatic stress disorder
• palliative care

• Pediatric Hematology-Oncology, Dana-Farber Cancer Institute, Boston, USA

  Christine N. Duncan

• Children’s Hospital of Wisconsin-Milwaukee, Medical College of Wisconsin, Milwaukee, USA

  Julie-An M. Talano

• Department of Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, USA

  Jennifer A. McArthur

Christine N. Duncan, MD
Dana-Farber Cancer Institute
Pediatric Stem Cell Transplant Center
Boston, MA
USA


Julie-An M. Talano, MD
Medical College of Wisconsin
Children's Hospital of Wisconsin-Milwakee
Milwaukee, WI 
USA


Jennifer McArthur, DO
St. Jude Children’s Research Hospital
Department of Pediatric Medicine
Memphis, TN
USA

Policies and ethics