Editors:
- Serves as a "how to" manual for the initiation of drug discovery efforts
- Provides step-by-step detail essential for reproducible results
- Contains key tips and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1053)
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Table of contents (17 protocols)
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Front Matter
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Back Matter
About this book
Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one “how to” manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making “go/no-go” decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results.
Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts.
Editors and Affiliations
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Sanford Children's Health Research Ctr., Sanford-Burnham Medical Research Inst., La Jolla, USA
José Luis Millán
Bibliographic Information
Book Title: Phosphatase Modulators
Editors: José Luis Millán
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-562-0
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2013
Hardcover ISBN: 978-1-62703-561-3Published: 17 July 2013
Softcover ISBN: 978-1-4939-6031-6Published: 23 August 2016
eBook ISBN: 978-1-62703-562-0Published: 17 July 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 315
Number of Illustrations: 30 b/w illustrations, 45 illustrations in colour
Topics: Pharmacology/Toxicology, Medicinal Chemistry, Pharmacy
Industry Sectors: Biotechnology, Chemical Manufacturing, Consumer Packaged Goods, Health & Hospitals, Pharma