Editors:
- Fully updated with cutting-edge additions to the popular first edition
- Provides step-by-step reproducible laboratory protocols
- Contains tips on troubleshooting and avoiding known pitfalls
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 962)
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Table of contents (20 protocols)
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Front Matter
About this book
The second edition of p53 Protocols expands upon the first edition with progress in p53 research since the publication of the first edition. In p53 Protocols, Second Edition expert researchers in the field detail many of the methods that address the challenging questions of the p53 field. These methods include the identification of the target genes and binding partners of gain of function p53 mutants, methods to determine stress response, autophagy or senescence induced by p53, cell cycle analysis, analysis of different phases of DNA replication modified by p53, and generation of pluripotent stem cells. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
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Authoritative and practical, p53 Protocols, Second Edition seeks to aid scientists in the further study into p53 and other tumor suppressors.
Editors and Affiliations
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Massey Cancer Center, Department of Biochemistry, Virginia Commonwealth University, Richmond, USA
Sumitra Deb, Swati Palit Deb
Bibliographic Information
Book Title: p53 Protocols
Editors: Sumitra Deb, Swati Palit Deb
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-236-0
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2013
Hardcover ISBN: 978-1-62703-235-3Published: 13 November 2012
Softcover ISBN: 978-1-4939-5933-4Published: 23 August 2016
eBook ISBN: 978-1-62703-236-0Published: 13 November 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: X, 238
Topics: Protein Science
Industry Sectors: Biotechnology, Pharma