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TRP Channels in Drug Discovery

Volume II

  • Arpad Szallasi
  • Tamás Bíró

Part of the Methods in Pharmacology and Toxicology book series (MIPT)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. TRPs and Cardiovascular Disease

    1. Front Matter
      Pages 1-1
    2. José C. González-Cobos, Xuexin Zhang, Rajender K. Motiani, Kelly E. Harmon, Mohamed Trebak
      Pages 3-40
    3. Xiaojing Sun, Xiaolei Xu
      Pages 41-54
    4. Luciana Aparecida Campos, Ovidiu Constantin Baltatu
      Pages 91-99
  3. TRPs and the Brain

    1. Front Matter
      Pages 113-113
    2. Antonio Reboreda
      Pages 115-140
    3. Caitlin J. Riebe, Carsten T. Wotjak
      Pages 167-185
    4. Jennifer L. McGuire, Jennifer L. Coyner, Luke R. Johnson
      Pages 187-202
    5. Stephen W. White, Kenneth J. Sufka
      Pages 203-210
    6. Ryan C. Turner, Alisa S. Elliott, Jason D. Huber, Charles L. Rosen
      Pages 211-229
    7. Robert J. Gasperini, Lisa Foa
      Pages 239-252
  4. TRPs and Skin

    1. Front Matter
      Pages 253-253
    2. Heike Benecke, Janine Wäring, Tobias Lotts, Sonja Ständer
      Pages 255-277
    3. Laurent Misery
      Pages 279-285
    4. Michael P. Philpott
      Pages 287-299
  5. TRPs and Metabolic Disorders

    1. Front Matter
      Pages 301-301
    2. Anish Suri, Matteo Levisetti
      Pages 303-318
    3. Dorte X. Gram
      Pages 319-332
    4. Angela M. Gajda, Michael A. Pellizzon, Matthew R. Ricci
      Pages 333-350
    5. Sharon C. Cheetham, Helen C. Jackson
      Pages 351-376
  6. TRPs: Colitis, Cancer, Thermosensation, and Musculoskeletal Disorders

    1. Front Matter
      Pages 377-377
    2. Patrick A. Hughes, Stuart M. Brierley, Joel Castro, Andrea M. Harrington, L. Ashley Blackshaw
      Pages 379-390
    3. V’yacheslav Lehen’kyi, Sergii Khalimonchyk, Albin Pourtier, Maylis Raphaël, Natalia Prevarskaya
      Pages 391-399
    4. Kata Bölcskei
      Pages 401-417
    5. Michael F. Crutchlow, Joel D. Greenspan
      Pages 419-436
    6. Katalin Sandor, Kutty Selva Nandakumar, Rikard Holmdahl, Camilla I. Svensson
      Pages 437-455
    7. Yuko Iwata, Shigeo Wakabayashi
      Pages 457-478
  7. Back Matter
    Pages 479-489

About this book

Introduction

Recent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention.  TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field.  Volume II presents practical methodologies involving models for disorders of the cardiovascular system, the brain, skin, the metabolic system, as well as colitis, cancer, thermosensation, and musculoskeletal disorders.  Written for the Methods in Pharmacology and Toxicology™ series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab.

 

Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.

Keywords

Brain disorders Cardiovascular disease Drug discovery Ion channels Metabolic disorders Pharmaceuticals Preclinical development TRP channelopathies Transient Receptor Potential channels

Editors and affiliations

  • Arpad Szallasi
    • 1
  • Tamás Bíró
    • 2
  1. 1.Transfusion ServicesMonmouth Medical CenterLong BranchUSA
  2. 2.Department of PhysiologyUniversity of Debrecen Medical and Health Science CenterDebrecenHungary

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-62703-095-3
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-094-6
  • Online ISBN 978-1-62703-095-3
  • Series Print ISSN 1557-2153
  • Series Online ISSN 1940-6053
  • Buy this book on publisher's site
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