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Telomeres and Telomerase

Methods and Protocols

  • Zhou Songyang

Part of the Methods in Molecular Biology book series (MIMB, volume 735)

Table of contents

  1. Front Matter
    Pages i-x
  2. Zhou Songyang
    Pages 1-11
  3. Isabelle Ourliac-Garnier, Arturo Londoño-Vallejo
    Pages 21-31
  4. Isabelle Ourliac-Garnier, Arturo Londoño-Vallejo
    Pages 33-46
  5. Yong Zhao, Jerry W. Shay, Woodring E. Wright
    Pages 47-54
  6. Yong Zhao, Jerry W. Shay, Woodring E. Wright
    Pages 63-75
  7. Raveendra I. Mathad, Danzhou Yang
    Pages 77-96
  8. Eli S. Williams, Michael N. Cornforth, Edwin H. Goodwin, Susan M. Bailey
    Pages 113-124
  9. Eladio Abreu, Rebecca M. Terns, Michael P. Terns
    Pages 125-137
  10. Asha S. Multani, Sandy Chang
    Pages 139-143
  11. Rekha Rai, Sandy Chang
    Pages 145-150
  12. Back Matter
    Pages 189-191

About this book

Introduction

New and rapid advances in technology have equipped us with a variety of tools and platforms to ask fundamental questions of telomere regulation and have allowed investigators to carry out experiments using diverse model systems.  For example, proteomic, genomic, and molecular approaches have afforded us unprecedented insight into the complex protein interaction networks at work on the telomere chromatin and the detailed information regarding telomere dynamics in response to stress or stimuli.  Telomeres and Telomerase: Methods and Protocols, Second Edition builds upon the telomerase assays featured in the popular first edition to encompass many different assays that allow investigators to query the function of telomere proteins and the responses of the telomere DNA, including detailed examinations of biochemical, molecular, and proteomic approaches.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, Telomeres and Telomerase: Methods and Protocols, Second Edition serves as an ideal, up-to-date guide for investigators further pursing this vital field of study.

Keywords

Cancer progression Cell growth Chromatin Genomics Model systems Protein interaction networks Proteomics Telomere DNA Telomere regulation

Editors and affiliations

  • Zhou Songyang
    • 1
  1. 1., Dept. Biochemistry & Molecular BiologyBaylor College of MedicineHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-61779-092-8
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-091-1
  • Online ISBN 978-1-61779-092-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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