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Systems Biology in Drug Discovery and Development

Methods and Protocols

  • Book
  • © 2010

Overview

  • Focuses on translational methods through applying systems biology approaches directly in drug development and clinical practice
  • Aims toward the goal of truly personalized medicine
  • Features expert tips from successful labs from around the world

Part of the book series: Methods in Molecular Biology (MIMB, volume 662)

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Table of contents (17 chapters)

Keywords

About this book

Due to the failing “one-drug-fits-all” model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.

Reviews

From the reviews:

“This book describes state-of-the-art technologies and methods in molecular biology and the necessary integration of data … . The resultant book provides an effective resource for students, biologists, and physicians in multiple disciplines, as well as individuals involved in the drug development process. … This is a very effective and comprehensive guide to the advances in molecular biology methods and computational tools that model complex biological systems as a means to better understand disease mechanisms and identify appropriate drug candidates for individualized therapies.” (Rachel Renee Chennault, Doody’s Review Service, February, 2011)

Editors and Affiliations

  • PharmTao, Santa Clara, USA

    Qing Yan

Bibliographic Information

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