Comparative Genomics

  • Nicholas H. Bergman

Part of the Methods In Molecular Biology™ book series (MIMB, volume 396)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Comparative Analysis of Domain and Protein Families

    1. Front Matter
      Pages 1-1
    2. Philipp Pagel, Normann Strack, Matthias Oesterheld, Volker Stümpflen, Dmitrij Frishman
      Pages 3-15
    3. Sophie Pasek
      Pages 17-29
    4. Jaina Mistry, Robert Finn
      Pages 43-58
    5. Nicola Mulder, Rolf Apweiler
      Pages 59-70
    6. Kiyoko F Aoki-Kinoshita, Minoru Kanehisa
      Pages 71-91
  3. Orthologs, Synteny, and Genome Evolution

    1. Front Matter
      Pages 93-93
    2. Giulio Pavesi, Graziano Pesole
      Pages 111-119
    3. Lung Lu Chin, Chih Lin Ying, Lin Huang Yen, Yi Tang Chuan
      Pages 121-134
    4. Aaron E Darling, Todd J Treangen, Xavier Messeguer, Nicole T Perna
      Pages 135-152
    5. Volker Brendel, Stefan Kurtz, Xioakang Pan
      Pages 153-163
    6. Thomas Schmidt, Jens Stoye
      Pages 165-182
  4. Experimental Analysis of Whole Genomes: Analysis of Copy Number and Sequence Polymorphisms

    1. Front Matter
      Pages 183-183
    2. Paul van den IJssel, Bauke Ylstra
      Pages 207-221
    3. Eduardo N. Taboada, Christian C. Luebbert, John H.E. Nash
      Pages 223-253

About this book


Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press.


DNA Evolution Genotyp Microarray Nucleotide SNP Single Nucleotide Polymorphism genes hybridization proteins

Editors and affiliations

  • Nicholas H. Bergman
    • 1
  1. 1.Bioinformatics Program and Department of Microbiology and ImmunologyUniversity of Michigan Medical SchoolAnn Arbor

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-934115-37-4
  • Online ISBN 978-1-59745-515-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book
Industry Sectors
Chemical Manufacturing
Consumer Packaged Goods