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  • Book
  • © 2017

The Molecular Basis of Human Cancer

Editors:

  1. William B. Coleman

    1. Department of Pathology and Laboratory Medicine, Curriculum in Toxicology, UNC Program in Translational Medicine, UNC Lineberger Comprehensive Center, University of North Carolina School of Medicine, Chapel Hill, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Gregory J. Tsongalis

    1. Laboratory for Clinical Genomics and Advanced Technology (CGAT), Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, Hanover, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Written by experts in the field

  • Updated and revised to include current research

  • Richly illustrated

  • Includes supplementary material: sn.pub/extras

Sections

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eBook USD 169.00
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Softcover Book USD 219.99
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Hardcover Book USD 219.99
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Table of contents (43 chapters)

  1. Front Matter

    Pages i-xix
    PDF

  2. Cancer Epidemiology: Incidence and Etiology of Human Neoplasms

    • William B. Coleman, Gregory J. Tsongalis
    Pages 1-24

  3. Essential Concepts and Techniques in Molecular Biology

    • Claudine L. Lefferts, Joel A. Lefferts
    Pages 25-42

  4. Cancer Genomics

    • Jonathan R. Pollack
    Pages 43-63

  5. Cancer Cytogenetics

    • Thomas Ried, Kerstin Heselmeyer-Haddad, Jordi Camps, Timo Gaiser
    Pages 65-82

  6. Epigenetic Basis of Human Cancer

    • Thomas Mikeska, Alexander Dobrovic
    Pages 83-102

  7. Cancer Proteomics

    • Jeffrey M. Lake, Timothy D. Veenstra
    Pages 103-119

  8. An Overview of Cancer Genes

    • Ashley G. Rivenbark
    Pages 121-142

  9. Oncogenes and the Initiation and Maintenance of Tumorigenesis

    • Dean W. Felsher, Constadina Arvanitis, Pavan Bendapudi, Pavan Bachireddy
    Pages 143-157

  11. Senescence, Apoptosis, and Cancer

    • Manjari Dimri, Goberdhan P. Dimri
    Pages 183-196

  12. Novel Cancer Therapies Targeting Angiogenesis

    • Monte S. Willis, Nancy Klauber-DeMore
    Pages 197-202

  13. Beyond the Primary Tumor: Progression, Invasion, and Metastasis

    • Danny R. Welch, Douglas R. Hurst
    Pages 203-216

  14. Simple Sequence Mutations

    • Christophe Béroud
    Pages 217-230

  15. Single Nucleotide Polymorphisms and Cancer Susceptibility

    • Richard A. Hubner, Richard S. Houlston
    Pages 231-239

  16. Chromosomes and Chromosomal Instability in Human Cancer

    • Kazuma Ohyashiki, Masahiko Kuroda, Junko H. Ohyashiki
    Pages 241-262

  17. Epigenetic Mechanisms in Cancer Development

    • José Ignacio Martín-Subero, Manel Esteller
    Pages 263-275

  18. MicroRNAs and Cancer

    • Phong Trang, Joanne B. Weidhaas, Frank J. Slack
    Pages 277-286

  20. Viral Mechanisms in Human Carcinogenesis

    • Paul F. Lambert
    Pages 297-306
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About this book

This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care.


The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.


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Keywords

  • Sporadic Cancer
  • Cancer Genomics
  • Hormonal Carcinogenesis
  • Hereditary Cancer
  • Cancer Drug Discovery
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Editors and Affiliations

  • Department of Pathology and Laboratory Medicine, Curriculum in Toxicology, UNC Program in Translational Medicine, UNC Lineberger Comprehensive Center, University of North Carolina School of Medicine, Chapel Hill, USA

    William B. Coleman

  • Laboratory for Clinical Genomics and Advanced Technology (CGAT), Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, Hanover, USA

    Gregory J. Tsongalis

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About the editors

William B. Coleman
Department of Pathology and Laboratory medicine, Curriculum in 
Toxicology, Program in Translational Medicine, UNC Lineberger 
Comprehensive Center, University of North Carolina School of Medicine, 
Chapel Hill, NC


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Bibliographic Information

  • Book Title: The Molecular Basis of Human Cancer

  • Editors: William B. Coleman, Gregory J. Tsongalis

  • DOI: https://doi.org/10.1007/978-1-59745-458-2

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2017

  • Hardcover ISBN: 978-1-934115-18-3Published: 13 November 2016

  • Softcover ISBN: 978-1-4939-9156-3Published: 12 December 2018

  • eBook ISBN: 978-1-59745-458-2Published: 11 November 2016

  • Edition Number: 2

  • Number of Pages: XIX, 873

  • Number of Illustrations: 97 b/w illustrations, 120 illustrations in colour

  • Topics: Oncology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Finance, Business & Banking, Health & Hospitals, Pharma

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Access via your institution

Buy it now

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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