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  • Book
  • © 2008

Molecular Genetic Pathology

  • Provides useful and up to date references, principles, and explanations including relevant information to the clinical practice

  • Thorough review book for medical genetics and molecular genetic pathology

  • Organized and detailed text of specific molecular genetic techniques

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-59745-405-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout

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Table of contents (31 chapters)

  1. Front Matter

    Pages i-xii
  2. General Sections

    1. Front Matter

      Pages 1-1
    2. Principles of Clinical Molecular Biology

      • Shaobo Zhang, Darrell D. Davidson, David Y. Zhang, Jodi A. Parks, Liang Cheng
      Pages 3-32
    3. Principles of Clinical Cytogenetics

      • Stuart Schwartz
      Pages 33-63
    4. Diagnostic Methodology and Technology

      • Josephine Wu, Tao Feng, Ruliang Xu, Fei Ye, Bruce E. Petersen, Liang Cheng et al.
      Pages 65-131
    5. Tissue Microarrays and Biomarker Validation

      • Martina Storz, Holger Moch
      Pages 133-140
    6. Laser Capture Microdissection

      • Matthew Kuhar, Liang Cheng
      Pages 141-154
    7. Clinical Flow Cytometry

      • Magdalena Czader
      Pages 155-183
    8. Conceptual Evolution in Cancer Biology

      • Shaobo Zhang, Darrell D. Davidson, Liang Cheng
      Pages 185-208
    9. Clinical Genomics in Oncology

      • Hugo M. Horlings, Marc Van de Vijver
      Pages 209-229
    10. Clinical Proteomics

      • David H. Geho, Virginia Espina, Lance A. Liotta, Emanuel F. Petricoin, Julia D. Wulfkuhle
      Pages 231-239
    11. Clinical Pharmacogenomics

      • Catalina Lopez-Correa, Lawrence M. Gelbert
      Pages 241-259
    12. Clonality Analysis in Modern Oncology and Surgical Pathology

      • Liang Cheng, Shaobo Zhang, Timothy D. Jones, Deborah E. Blue
      Pages 261-301
    13. Instrumentation

      • Bruce E. Petersen, Josephine Wu, Liang Cheng, David Y. Zhang
      Pages 365-392
    14. Genetic Inheritance and Population Genetics

      • Tatiana Foroud, Daniel L. Koller
      Pages 393-403
    15. Genetic Counseling

      • Kimberly A. Quaid, Lisa J. Cushman
      Pages 405-413
  3. Disease-Based Sections

    1. Front Matter

      Pages 415-415
    2. Molecular Medical Genetics

      • Lisa Edelmann, Stuart Scott, Ruth Kornreich
      Pages 417-440
    3. Prenatal Diagnosis

      • Nataline Kardon, Lisa Edelmann
      Pages 441-448

About this book

Molecular Genetic Pathology presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Part I examines the clinical areas of molecular biology, genomics, pharmacogenomics and proteomics, while Part II covers the molecular areas of medical genetics, microbiology, hematology, transfusion medicine, oncology and forensic pathology. The volume provides a unique reference for the practicing pathologist and medical geneticist as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

Keywords

  • Cytogenetics
  • Fluoreszenz in situ-Hybridisierung
  • Microarray
  • Molecular Pathology
  • gene therapy
  • genes
  • genetics
  • hybridization
  • tissue

Reviews

From the reviews:

"A compilation of genetic tests and related information … . This book would be of great interest to molecular genetics fellows, pathology/laboratory medicine residents or fellows, practicing pathologists, and oncologists. It would also be of interest to anyone in the healthcare professions … . I also recommend it to practitioners looking for a comprehensive and concise, state-of-the-art book on clinically useful molecular/genetic tests. It is a great study guide during training and would be a great review book in preparation for specialty board certification exams." (Valerie L. Ng, Doody’s Review Service, July, 2008)

"This book provides a comprehensive review of the various molecular genetic tests that are currently being conducted at research and clinical laboratories.  This textbook is robust and would be useful in an advanced genetics course ase part of a clinical-based diagnosic genetics-based graduate program; genetic training postdoctoral program, or molecular genetic pathology post-MD fellowship training program.  In addition, some of the chapters in this book could be incorporated into existing advanced cytogenetic courses or upper-level molecular biology courses.

In summary, Molecular Genetic Pathology is a comprehensive review guide that looks at the various theories and methodologies of how molecular genetic testing is being performed." (Reviewed by Peter Hu, Molecular Genetic Technology Program, The University of Texas M.D. Anderson Cancer Center, Houston, Texas)

"The book features chapters written by experts in all aspects of molecular pathology … . this is a timely and useful book, principally because of its comprehensiveness. Readers seeking an introduction to molecular diagnostics will probably find it thin on background explanations and overwhelming in detail. … for trainees and laboratory workers in the field who need a quick summary of available techniques and diagnostic markers, it should prove to be a valuable and convenient resource." (Jeffrey Sklar, The New England Journal of Medicine, Vol. 360 (20), May, 2009)

Editors and Affiliations

  • Department of Pathology and Laboratory Medicine and Clarian Pathology Laboratory, Indiana University School of Medicine, Indianapolis

    Liang Cheng

  • Department of Pathology, Mount Sinai School of Medicine, New York

    David Y. Zhang

  • Mount Sinai Medical Center, New York

    David Y. Zhang

Bibliographic Information

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-59745-405-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout