Linkage Disequilibrium and Association Mapping

Analysis and Applications

  • Andrew R. Collins

Part of the Methods in Molecular Biology™ book series (MIMB, volume 376)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Andrew R. Collins
    Pages 1-15
  3. Newton E. Morton
    Pages 17-21
  4. Tai-Yue Kuo, Winston Lau, Andrew R. Collins
    Pages 47-57
  5. Sudha K. Iyengar, Robert C. Elston
    Pages 71-84
  6. Andrew DeWan, Robert J. Klein, Josephine Hoh
    Pages 85-107
  7. Yin Yao Shugart, Lina Chen, Rui Li, Terri Beaty
    Pages 141-149
  8. Emily L. Webb, Richard S. Houlston
    Pages 151-159
  9. Hsin-Chou Yang, Cathy S. J. Fann
    Pages 161-175
  10. Tarja Laitinen
    Pages 213-234
  11. Eleftheria Zeggini, Mark I. McCarthy
    Pages 235-250
  12. Back Matter
    Pages 251-255

About this book

Introduction

As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In Linkage Disequilibrium and Association Mapping: Analysis and Applications, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike.

The volume comprises four general sections: the first presents an overview and historical basis of the subject. The second section considers the developing methodology and recent findings from studies which have characterized the genome-wide linkage disequilibrium structure in enormous detail. The following section examines all aspects of disease association mapping methodology, and the final two chapters review the early successes in mapping genes involved in two of the most important human diseases: asthma and type 2 diabetes.

Keywords

Allele DNA SNP gene genes genome

Editors and affiliations

  • Andrew R. Collins
    • 1
  1. 1.Genetic Epidemiology and Bioinformatics GroupHuman Genetics Division Southampton General HospitalSouthamptonUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-389-9
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-669-6
  • Online ISBN 978-1-59745-389-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book
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