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  • Book
  • © 2009

Clinical Epidemiology

Practice and Methods

  • Presents the basic science of practicing physicians and allied health professionals
  • Focuses on determination of diagnosis, prognosis, and management of human disease
  • Outlines the concepts and methods of patient-related research, with an emphasis on research design, measurement, and evaluation
  • Provides a primer on assessing multiple studies to better inform clinical decisionmaking
  • Written by practicing physicians who are active in clinical research

Part of the book series: Methods in Molecular Biology (MIMB, volume 473)

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Table of contents (18 protocols)

  1. Front Matter

    Pages i-x
  2. Modeling Longitudinal Data, I: Principles of Multivariate Analysis

    • Pietro Ravani, Brendan Barrett, Patrick Parfrey
    Pages 39-60
  3. Modeling Longitudinal Data, II: Standard Regression Models and Extensions

    • Pietro Ravani, Brendan Barrett, Patrick Parfrey
    Pages 61-94
  4. The Design of Randomized Controlled Trials

    • Bryan M. Curtis, Brendan J. Barrett, Patrick S. Parfrey
    Pages 95-111
  5. Evaluation of Diagnostic Tests

    • John M. Fardy
    Pages 127-136
  6. Biomarkers and Surrogates in Clinical Studies

    • Claudio Rigatto, Brendan J. Barrett
    Pages 137-154
  7. Measurement and Analysis of Patient-Reported Outcomes

    • Klemens B. Meyer, Kimberly A. Clayton
    Pages 155-169
  8. Bias in Clinical Studies of Genetic Diseases

    • Susan Stuckless, Patrick S. Parfrey
    Pages 171-186
  9. Genetic Epidemiology of Complex Phenotypes

    • Lynette Peddle, Proton Rahman
    Pages 187-201
  10. Qualitative Research in Clinical Epidemiology

    • Deborah M. Gregory, Christine Y. Way
    Pages 203-215
  11. Primer on Systematic Review and Meta-Analysis

    • Marcello Tonelli, Dan Hackam, Amit X. Garg
    Pages 217-233
  12. Basics of Health Technology Assessment

    • Daria OReilly, Kaitryn Campbell, Ron Goeree
    Pages 263-283
  13. Research Ethics for Clinical Researchers

    • John D. Harnett, Richard Neuman
    Pages 285-297
  14. Budgeting, Funding and Managing Clinical Research Projects

    • Elizabeth Hatfield, Elizabeth Dicks, Patrick Parfrey
    Pages 299-311
  15. Back Matter

    Pages 313-321

About this book

Clinical epidemiology provides the scientific basis for the practice of medicine due to its focus on the diagnosis, prognosis and management of human disease using appropriate research design, measurement and evaluation.  In Clinical Epidemiology: Practice and Methods, leading experts contribute selections intended to educate researchers on how best to undertake clinical research.  Divided into two categories, the volume first covers issues of design, measurement and analysis associated with various research designs, then continues with methods to better inform medical decision-making, including aggregation of multiple studies using meta-analysis, health economics, clinical practice guidelines and health technology assessment.  As a part of the highly successful Methods in Molecular Biologyâ„¢ series, this comprehensive text collects the kind of detailed, up-to-date information and implementation advice that is crucial for getting optimal results.

Essential and advantageous, Clinical Epidemiology: Practice and Methods is an ideal reference for medical practitioners, basic scientists and allied health professionals who desire to improve clinical outcomes.

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access