Diabetes and Cardiovascular Disease

1. Front Matter

   Pages i-xiii

   PDF

2. Pathophysiology

   1. Front Matter

      Pages 1-1

      PDF

   2. The Metabolic Syndrome and Vascular Disease

      • Aresh J. Anwar, Anthony H. Barnett, Sudhesh Kumar

      Pages 3-22

   3. Effects of Insulin on the Vascular System

      • Helmut O. Steinberg

      Pages 23-43

   4. Effect of Diabetes on Endothelial Function

      • Keiko Naruse, George L. King

      Pages 45-64

   5. Vascular Abnormalities in the Prediabetic State

      • A. Enrique Caballero, Su Chi Lim, Edward S. Horton, Aristidis Veves

      Pages 65-80

   6. Diabetes and Advanced Glycation End Products

      • Helen Vlassara

      Pages 81-102

   7. The Renin-Angiotensin System in Diabetic Cardiovascular Complications

      • Edward P. Feener

      Pages 103-121

   8. Diabetes and Hypertension

      • James R. Sowers

      Pages 123-129

   9. Diabetes and Dyslipidemia

      • Henry N. Ginsberg, Catherine Tuck

      Pages 131-147

   10. Diabetes and Thrombosis

       • David J. Schneider, Burton E. Sobel

       Pages 149-168

   11. Diabetes and Atherosclerosis

       • Maria F. Lopes-Virella

       Pages 169-194

   12. Animal Models of Diabetes and Atherosclerosis

       • Peter D. Reaven, Wulf Palinski

       Pages 195-212

   13. Nitric Oxide and Its Role in Diabetes Mellitus

       • Michael T. Johnstone, Todd A. Caulfield

       Pages 213-236

   14. Plasminogen Activator Inhibitor-1 and Vascular Disease in Diabetes Mellitus

       • Douglas E. Vaughan

       Pages 237-243

3. The Heart

   1. Front Matter

      Pages 245-245

      PDF

   2. Coronary Artery Disease in Diabetes

      • Doron Aronson, Michael T. Johnstone

      Pages 247-279

   3. Heart Failure in Diabetic Patients

      • Lawrence H. Young, Raymond R. Russell III, Deborah Chyun, Tarik Ramahi

      Pages 281-297

   4. Preoperative Assessment and Perioperative Management of the Surgical Patient with Diabetes Mellitus

      • Theodoros Laddis, Mylan C. Cohen

      Pages 299-326

4. Peripheral Vascular System

   1. Front Matter

      Pages 327-327

      PDF

With over ten million diagnosed patients and another five million undiagnosed, diabetes mellitus and its complications-cardiovascular disease, nephropathy, neuropathy, and retinopathy-is a major public health problem that will assume epidemic proportions as the population grows older. In Diabetes and Cardiovascular Disease, Michael T. Johnstone, md, and Aristidis Veves, md, dsc, have assembled a panel of seasoned clinicians and expert scientists to comprehensively review both the clinical and scientific aspects of diabetic cardiovascular disease. The contributors thoroughly discuss the mechanisms and risk factors of diabetes in relation to hypertension, dyslipidemia, thrombosis, atherosclerosis, coronary artery disease, and congestive heart failure. Their review includes a full examination of the epidemiology, mechanisms, methods of assessment, and treatment of the disease at the macrovascular level, and a discussion of its microvascular effects, including retinopathy, nephropathy, neuropathy, and compromised microcirculation in the diabetic foot. Each chapter covers its topics in great detail and is accompanied by extensive references.
Comprehensive and up-to-date, Diabetes and Cardiovascular Disease offers not only practicing physicians the day-to-day practical knowledge needed to treat patients effectively, but also clinical scientists a deeper understanding for developing novel therapies for this devastating illness.

• Diabetes
• Diabetes mellitus
• atherosclerosis
• cardiovascular
• circulation
• coronary artery disease
• heart
• hypertension
• insulin
• vascular disease

"All practicing clinicians would find some value in this text, but especially cardiologists and internal medicine practitioners as well as vascular specialists. Family medicine physicians and medical students would find it a good reference. . .This is indeed a comprehensive review of the vascular implications of diabetes. It is an important book because of the increasing prevalence of diabetes in our society. The book provides a good starting point for researchers since one can be struck after reading it that there are many opportunities for investigatioin presented here. It is a worthwhile addition to the medical literature. "-Doody's Health Sciences Book Review Journal

"...covers the range of problems, both clinical and biochemical, that arise in the cardiovascular system of those with diabetes. I highly recommend the book to interested medical students and residents and all clinicians who work with patients with diabetes." - Canadian Family Physician

• Beth Israel Deaconess Medical Center, Boston, USA

  Michael T. Johnstone, Aristidis Veves

• Harvard Medical School, Boston, USA

  Michael T. Johnstone, Aristidis Veves

Policies and ethics