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Basic Neurobiology Techniques

  • Book
  • © 2020

Overview

Editors:
  1. Nicholas J. D. Wright

    1. Levine College of Health Sciences, Wingate University, Wingate, USA

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 152)

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Table of contents (13 protocols)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Semiconductor Quantum Dots for Visualization and Sensing in Neuronal Cell Systems

    • Lauren D. Field, Yung Chia Chen, James B. Delehanty
    Pages 1-18

  3. Injection of Adeno-Associated Virus Containing Optogenetic and Chemogenetic Probes into the Neonatal Mouse Brain

    • Nhan C. Huynh, Baher A. Ibrahim, Christopher M. Lee, Mickeal N. Key, Daniel A. Llano
    Pages 19-43

  4. Guide to Transcranial Imaging of Sound-Evoked Activity in the Auditory Cortex of GCaMP6s Mice In Vivo

    • Georgiy Yudintsev, Christopher M. Lee, Alexander R. Asilador, Daniel A. Llano
    Pages 45-68

  5. A Novel Preclinical Rat Model of Alzheimer’s Disease

    • Karim A. Alkadhi
    Pages 69-98

  6. Using Zebrafish to Study and Visualize Barriers of the CNS

    • Robyn Anne Umans
    Pages 99-129

  7. Photometric Patch Electrode to Simultaneously Measure Neural Electrical Activity and Optical Signal in the Brain Tissue

    • Harunori Ohmori
    Pages 131-153

  8. Patch-Clamp Fluorometry and Its Applications to the Study of Ion Channels

    • Esteban Suárez-Delgado, León D. Islas
    Pages 155-183

  9. Modeling Early-Onset Postischemic Seizures in Adult and Aging Mice

    • Liang Zhang, Chiping Wu, Justin Wang
    Pages 185-212

  10. Modeling Psychological Trauma in Rats

    • Samina Salim
    Pages 213-233

  11. Extending the Life Span of Acute Neuronal Tissue for Imaging and Electrophysiological Studies

    • Yossi Buskila, Alba Bellot-Saez, Orsolya Kékesi, Morven Cameron, John Morley
    Pages 235-259

  12. Confocal Imaging of Fast Flash Photolysis of Caged Compounds in Cultured Neurons

    • Eduard Korkotian, Menahem Segal
    Pages 261-284

  13. Analysis of the Functional States of an Astrocyte Syncytium

    • Yixing Du, Conrad M. Kiyoshi, David Terman, Min Zhou
    Pages 285-313

  14. Assessment of Behavioral Dysfunction Following Experimental Traumatic Brain Injury (TBI)

    • Shruti V. Kabadi, Kimberly R. Byrnes
    Pages 315-349

  15. Back Matter

    Pages 351-352
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Keywords

About this book

This volume explores the latest techniques and improved methods used to study important neurobiological and associated neuropathological conditions. Chapters cover topics such as the application of semiconductor quantum dots as photostable fluorophores used for labeling and tracking; GCaMP6 transcranial imaging to monitor neural activity; the patch-clamping technique allowing simultaneous monitoring of membrane currents and optical signals; and quantifying behavioral dysfunction caused by traumatic brain injury (TBI). In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and practical, Basic Neurobiology Techniques is a valuable resource for novel and expert researchers interested in expanding their knowledge of this developing field.  


Editors and Affiliations

  • Levine College of Health Sciences, Wingate University, Wingate, USA

    Nicholas J. D. Wright

Bibliographic Information

  • Book Title: Basic Neurobiology Techniques

  • Editors: Nicholas J. D. Wright

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-9944-6

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2020

  • Hardcover ISBN: 978-1-4939-9943-9Published: 02 November 2019

  • Softcover ISBN: 978-1-4939-9946-0Published: 02 November 2020

  • eBook ISBN: 978-1-4939-9944-6Published: 01 November 2019

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XII, 352

  • Number of Illustrations: 23 b/w illustrations, 106 illustrations in colour

  • Topics: Neurosciences, Neurobiology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

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