Skip to main content
SpringerLink
Log in
Book cover

Cancer Epigenetics for Precision Medicine

Methods and Protocols

  • Book
  • © 2018

Overview

Editors:
  1. Ramona G. Dumitrescu

    1. Kelly Government Solutions, Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Mukesh Verma

    1. Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1856)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (18 protocols)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Early Epigenetic Changes and New Epigenetic Targets in Different Types of Cancers

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Early Epigenetic Markers for Precision Medicine

      • Ramona G. Dumitrescu
      Pages 3-17

    3. Interplay Between Genetic and Epigenetic Changes in Breast Cancer Subtypes

      • Ramona G. Dumitrescu
      Pages 19-34

    4. Role of Microbiome in Carcinogenesis Process and Epigenetic Regulation of Colorectal Cancer

      • Lulu Farhana, Hirendra Nath Banerjee, Mukesh Verma, Adhip P. N. Majumdar
      Pages 35-55

    5. Epigenome-Based Precision Medicine in Lung Cancer

      • Dongho Kim, Duk-Hwan Kim
      Pages 57-85

    6. Epigenetics in Hematological Malignancies

      • Nataly Cruz-Rodriguez, Alba L. Combita, Jovanny Zabaleta
      Pages 87-101

    7. MicroRNAs Role in Prostate Cancer

      • Ovidiu Balacescu, Ramona G. Dumitrescu, Catalin Marian
      Pages 103-117

  3. Contributing Environmental Factors to Epigenetic Changes Leading to Cancer Development

    1. Front Matter

      Pages 119-119
      Download chapter PDF

    2. Effects of Dietary Nutrients on Epigenetic Changes in Cancer

      • Nicoleta Andreescu, Maria Puiu, Mihai Niculescu
      Pages 121-139

    3. Diet, Microbiome, and Epigenetics in the Era of Precision Medicine

      • Gabriela Riscuta, Dan Xi, Dudith Pierre-Victor, Pamela Starke-Reed, Jag Khalsa, Linda Duffy
      Pages 141-156

    4. Alcohol-Induced Epigenetic Changes in Cancer

      • Ramona G. Dumitrescu
      Pages 157-172

    5. Epigenetic Basis of Circadian Rhythm Disruption in Cancer

      • Edyta Reszka, Shanbeh Zienolddiny
      Pages 173-201

    6. Epigenetic Changes of the Immune System with Role in Tumor Development

      • Irina Daniela Florea, Christina Karaoulani
      Pages 203-218

    7. DNA Methylation as a Biomarker of Aging in Epidemiologic Studies

      • Unhee Lim, Min-Ae Song
      Pages 219-231

    8. Challenges and Opportunities in Social Epigenomics and Cancer

      • Krishna Banaudha, Vineet Kumar, Mukesh Verma
      Pages 233-243

  4. Methods Used in Cancer Epigenomics

    1. Front Matter

      Pages 245-245
      Download chapter PDF

    2. Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology

      • Alok Mishra, Mukesh Verma
      Pages 247-254

    3. Methylation and MicroRNA Profiling to Understand Racial Disparities of Prostate Cancer

      • Hirendra Nath Banerjee, William Kahan, Vineet Kumar, Mukesh Verma
      Pages 255-267

    4. Analysis of DNA Hypermethylation in Pancreatic Cancer Using Methylation-Specific PCR and Bisulfite Sequencing

      • Bin Liu, Christian Pilarsky
      Pages 269-282
Back to top

Keywords

About this book

This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.

Editors and Affiliations

  • Kelly Government Solutions, Bethesda, USA

    Ramona G. Dumitrescu

  • Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, USA

    Mukesh Verma

Bibliographic Information

  • Book Title: Cancer Epigenetics for Precision Medicine

  • Book Subtitle: Methods and Protocols

  • Editors: Ramona G. Dumitrescu, Mukesh Verma

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-8751-1

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018

  • Hardcover ISBN: 978-1-4939-8750-4Published: 03 September 2018

  • Softcover ISBN: 978-1-4939-9383-3Published: 27 November 2019

  • eBook ISBN: 978-1-4939-8751-1Published: 03 September 2018

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 298

  • Number of Illustrations: 2 b/w illustrations, 12 illustrations in colour

  • Topics: Cancer Research

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

Publish with us

Policies and ethics

Back to top

Search

Navigation