Overview
A selection of key topics provide foundation information in mammalian spermatogonial biology
Highlights include spermatogonial stem cells, genome integrity, and therapeutic potentials
A key reference for researchers new to the field through to experienced scientists
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Table of contents (14 chapters)
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Spermatogenesis in Mammals
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Postnatal Development of the Spermatogonial Population
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Spermatogonial Stem Cells
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Spermatogonial Differentiation
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Genome Integrity of Spermatogonia
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Tools to Study Spermatogonial Biology
Keywords
About this book
Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals.
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Editors and Affiliations
About the editors
Jon M. Oatley, PhD, is Associate Professor and Director for the Center for Reproductive Biology, Washington State University.
Michael D. Griswold, PhD, is Regents Professor of Molecular Biosciences, Washington State University.
Bibliographic Information
Book Title: The Biology of Mammalian Spermatogonia
Editors: Jon M. Oatley, Michael D. Griswold
DOI: https://doi.org/10.1007/978-1-4939-7505-1
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media LLC 2017
Hardcover ISBN: 978-1-4939-7503-7Published: 22 November 2017
Softcover ISBN: 978-1-4939-8505-0Published: 05 September 2018
eBook ISBN: 978-1-4939-7505-1Published: 20 November 2017
Edition Number: 1
Number of Pages: XI, 387
Number of Illustrations: 3 b/w illustrations, 41 illustrations in colour
Topics: Molecular Medicine, Animal Physiology, Cell Biology, Human Physiology, Reproductive Medicine
Industry Sectors: Biotechnology, Chemical Manufacturing, Consumer Packaged Goods, Health & Hospitals, Pharma