Editors:
Includes cutting-edge methods and protocols
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1541)
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Table of contents (25 protocols)
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Front Matter
About this book
This volume provides readers with detailed protocols covering the main cancer cytogenetics techniques needed for clinical utilization and research purposes. The chapters in this book cover topics such as chromosome preparation for myeloid malignancies; chromosome bandings; fluorescence in situ hybridization probe preparation; array-based comparative genomic hybridization; and cytogenetic nomenclature and reporting. The updated reviews on chromosomal abnormalities in hematological malignancies are excellent guides for cytogenetics data interpretations and specific malignant diseases correlation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and comprehensive, Cancer Cytogenetics: Methods and Protocols is a valuable resource for the novice in cytogenetics because it provides helpful guiding protocols, but it’s also great for those who are already engaged in the field and are looking for some technical hints.
Keywords
- Array Comparative Genomic Hybridization (aCGH)
- FISH
- lymphoid
- myelodysplastic syndromes
- myeloid leukemia
- karyotyping
- chromosome bandings
- hybridization probe preparation
- data interpretations
Editors and Affiliations
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Haematology Division Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong Prince of Wales Hospital, Shatin, Hong Kong, China
Thomas S.K. Wan
Bibliographic Information
Book Title: Cancer Cytogenetics
Book Subtitle: Methods and Protocols
Editors: Thomas S.K. Wan
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-6703-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2017
Hardcover ISBN: 978-1-4939-6701-8Published: 01 December 2016
Softcover ISBN: 978-1-4939-8278-3Published: 07 July 2018
eBook ISBN: 978-1-4939-6703-2Published: 30 November 2016
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 340
Number of Illustrations: 34 b/w illustrations, 43 illustrations in colour
Topics: Cancer Research
Industry Sectors: Biotechnology, Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma