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Experimental Neurosurgery in Animal Models

  • Book
  • © 2016

Overview

Editors:
  1. Miroslaw Janowski

    1. Mossakowski Medical Research Centre, Department of Neurosurgery, Warsaw, Poland

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  • Focuses on surgical techniques rather than the diseases modeled by them
  • Presents in-depth analysis and instruction for the instrumentation
  • Examines targeted and specific issues for each methodology

Part of the book series: Neuromethods (NM, volume 116)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Animal Models of Traumatic Brain Injury

    • Fredrik Clausen
    Pages 1-12

  3. Experimental Radiosurgery in Animal Models

    • Ajay Niranjan, Wendy Fellows-Mayle, Douglas Kondziolka, L. Dade Lunsford
    Pages 13-29

  4. Stereotactic Surgery in Rats

    • Jaroslaw Maciaczyk, Ulf D. Kahlert, Máté Döbrössy, Guido Nikkhah
    Pages 31-54

  5. Rat Middle Cerebral Artery (MCA) Occlusion Models Which Involve a Frontotemporal Craniectomy

    • Hideaki Imai, Nobuhito Saito, I. Mhairi Macrae
    Pages 55-71

  6. Inferior Colliculus Approach in a Rat

    • Dennis T. T. Plachta
    Pages 73-84

  7. Why Robots Entered Neurosurgery

    • Jason W. Motkoski, Garnette R. Sutherland
    Pages 85-105

  8. Impact Model of Spinal Cord Injury

    • Dorothée Cantinieaux, Rachelle Franzen, Jean Schoenen
    Pages 107-110

  9. Acute Clip Compression Model of SCI

    • Jared T. Wilcox, Michael G. Fehlings
    Pages 111-117

  10. Microsurgical Approach to Spinal Canal in Rats

    • Mortimer Gierthmuehlen, Jan Kaminsky
    Pages 119-132

  11. Stereotaxic Injection into the Rat Spinal Cord

    • Charla C. Engels, Piotr Walczak
    Pages 133-140

  12. Surgical Access to Cisterna Magna Using Concorde-Like Position for Cell Transplantation in Mice and CNS Dissection within Intact Dura for Evaluation of Cell Distribution

    • Miroslaw Janowski
    Pages 141-149

  13. Animal Models for Experimental Neurosurgery of Peripheral and Cranial Nerves

    • Joachim Oertel, Christoph A. Tschan, Doerther Keiner
    Pages 151-163

  14. Surgery of the Brain and Spinal Cord in a Porcine Model

    • Jan Regelsberger
    Pages 165-173

  15. Real-Time Convection Delivery of Therapeutics to the Primate Brain

    • Dali Yin, Massimo S. Fiandaca, John Forsayeth, Krystof S. Bankiewicz
    Pages 175-194

  16. Focal Cerebral Ischemia by Permanent Middle Cerebral Artery Occlusion in Sheep: Surgical Technique, Clinical Imaging, and Histopathological Results

    • Björn Nitzsche, Henryk Barthel, Donald Lobsien, Johannes Boltze, Vilia Zeisig, Antje Y. Dreyer
    Pages 195-225

  17. A Nonhuman Primate Model of Delayed Cerebral Vasospasm After Aneurismal Subarachnoid Hemorrhage

    • Ryszard M. Pluta, John Bacher, Boris Skopets, Victoria Hoffmann
    Pages 227-250

  18. Back Matter

    Pages 251-255
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Keywords

About this book

This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.

Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.

Reviews

“This is an excellent sourcebook reference with respect to animal models of stroke, trauma, and neurodegenerative diseases. Rat models of Huntingtons, Parkinson’s, and epilepsy are discussed well. Sites for neurotoxin injections are diagrammed in a step by step approach. … A step by step approach is covered for each model introduced. This is a good book atlas for technicians, students, and research scientists.” (Joseph J. Grenier, Amazon.com, June, 2016)

Editors and Affiliations

  • Mossakowski Medical Research Centre, Department of Neurosurgery, Warsaw, Poland

    Miroslaw Janowski

Bibliographic Information

  • Book Title: Experimental Neurosurgery in Animal Models

  • Editors: Miroslaw Janowski

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-3730-1

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-3728-8Published: 08 June 2016

  • Softcover ISBN: 978-1-4939-8122-9Published: 26 May 2018

  • eBook ISBN: 978-1-4939-3730-1Published: 07 June 2016

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XIII, 255

  • Number of Illustrations: 56 b/w illustrations, 75 illustrations in colour

  • Topics: Neurosciences, Neurosurgery

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

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