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Post-Transcriptional Gene Regulation

Editors:

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1358)

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Table of contents (22 protocols)

  1. RNA Modifications

    1. Genome-Wide Analysis of A-to-I RNA Editing

      • Yiannis A. Savva, Georges St. Laurent, Robert A. Reenan
      Pages 255-268
    2. Nucleotide-Level Profiling of m5C RNA Methylation

      • Tennille Sibbritt, Andrew Shafik, Susan J. Clark, Thomas Preiss
      Pages 269-284
  2. Other Aspects of PTR

    1. Front Matter

      Pages 293-293
    2. Genome-Wide Identification of Alternative Polyadenylation Events Using 3′T-Fill

      • Stefan Wilkening, Vicent Pelechano, Lars M. Steinmetz
      Pages 295-302
    3. Genome-Wide Profiling of Alternative Translation Initiation Sites

      • Xiangwei Gao, Ji Wan, Shu-Bing Qian
      Pages 303-316
    4. Genome-Wide Study of mRNA Isoform Half-Lives

      • Joseph V. Geisberg, Zarmik Moqtaderi
      Pages 317-323
    5. Visualizing mRNA Dynamics in Live Neurons and Brain Tissues

      • Hye Yoon Park, Minho Song
      Pages 325-334
    6. Single-Molecule Live-Cell Visualization of Pre-mRNA Splicing

      • Robert M. Martin, José Rino, Ana C. de Jesus, Maria Carmo-Fonseca
      Pages 335-350
  3. Back Matter

    Pages 351-353

About this book

This volume aims to provide the most recent advances in techniques for studying gene expression regulation at the post-transcriptional level. Post-Transcriptional Gene Regulation, Second Edition is organized in six sections describing bioinformatics approaches for studying post-transcriptional regulation, various expression profiling approaches, protein-RNA interaction and non-coding RNA investigation techniques, methods for profiling RNA modifications, and other techniques such as alternative translation initiation or polyadenylation sites determination. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Post-Transcriptional Gene Regulation, Second Edition  is a versatile resource to researchers studying post-transcriptional regulation, introducing the most recent techniques and providing a comprehensive guide to their implementation.

Editors and Affiliations

  • Laboratory of Translational Genomics, Centre for Integrative Biology, University of Trento, Mattarello, Italy

    Erik Dassi

Bibliographic Information

  • Book Title: Post-Transcriptional Gene Regulation

  • Editors: Erik Dassi

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-3067-8

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-3066-1Published: 14 October 2015

  • Softcover ISBN: 978-1-4939-4969-4Published: 23 August 2016

  • eBook ISBN: 978-1-4939-3067-8Published: 13 October 2015

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XIII, 353

  • Number of Illustrations: 13 b/w illustrations, 30 illustrations in colour

  • Topics: Human Genetics, Gene Function

  • Industry Sectors: Biotechnology, Pharma

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access