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Inflammation and Lung Cancer

  • Steven M. Dubinett

Table of contents

  1. Front Matter
    Pages i-x
  2. Tonya C. Walser, Stacy J. Park, Jane Yanagawa, Steven M. Dubinett
    Pages 23-68
  3. Humam Kadara, Wilbur A. Franklin, Ignacio I. Wistuba
    Pages 69-93
  4. Alison K. Bauer, York E. Miller, Robert L. Keith
    Pages 95-136
  5. Tina El Rayes, Raul Catena, Shahin Rafii, Nasser Altorki, Vivek Mittal
    Pages 137-159
  6. Raphael Nemenoff, Miguel Gijon
    Pages 161-189
  7. Sherven Sharma, Siwen Hu-Lieskovan, Steven M. Dubinett, Jay Moon Lee
    Pages 191-209
  8. Back Matter
    Pages 211-212

About this book

Introduction

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This volume  presents aspects of the inflammatory tumor microenvironment (TME) and its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of microRNAs (miRNAs), and an increase in a stem cell phenotype. The volume also covers the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non-small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion, and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.

Keywords

Inflammation Lung cancer Micro-RNAs Non-small cell Tumor microenvironment

Editors and affiliations

  • Steven M. Dubinett
    • 1
  1. 1.David Geffen School of Medicine at UCLALos AngelesUSA

Bibliographic information

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