Gene Therapy for HIV and Chronic Infections

  • Ben Berkhout
  • Hildegund C.J. Ertl
  • Marc S. Weinberg

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 848)

Also part of the American Society of Gene & Cell Therapy book sub series (ASGCT, volume 848)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Monique M. A. Verstegen, Qiuwei Pan, Luc J. W. van der Laan
    Pages 1-29
  3. Kristie Bloom, Abdullah Ely, Patrick Arbuthnot
    Pages 31-49
  4. Lorea Blázquez, Puri Fortes
    Pages 51-69
  5. Elena Herrera-Carrillo, Ben Berkhout
    Pages 71-95
  6. Robert J. Scarborough, Anne Gatignol
    Pages 97-116
  7. Tatjana I. Cornu, Claudio Mussolino, Kristie Bloom, Toni Cathomen
    Pages 117-130
  8. Stephan J. Wu, Daniel O. Villarreal, Devon J. Shedlock, David B. Weiner
    Pages 131-148
  9. Bruce C. Schnepp, Philip R. Johnson
    Pages 149-167
  10. Sheena Saayman, Thomas C. Roberts, Kevin V. Morris, Marc S. Weinberg
    Pages 169-189
  11. Lisa Egerer, Hans-Peter Kiem, Dorothee von Laer
    Pages 191-209
  12. Mayumi Takahashi, John C. Burnett, John J. Rossi
    Pages 211-234
  13. Back Matter
    Pages 235-236

About this book

Introduction

This volume examines gene therapy and gene transfer approaches to preventing or treating chronic virus infections, focusing on the Big Three viral pathogens- HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV).  It explores molecular antiviral strategies, including RNA interference, aptamer-siRNA chimeras, U1i interference, editing CCR5, alternative genetic vaccination by intramuscular gene transfers of virus vectors, and HIV latency in the context of non-coding RNA. This title is a volume of the American Society of Gene and Cell Therapy, a sub-series of the highly successful Advances in Experimental Medicine and Biology. In eleven illustrated chapters, leading international researchers contextualize the structure, operation, and impact of pathogens; examine the existing genetic and molecular research; and extract possible methods of preventing and treating chronic viral infections while evaluating the current body of knowledge.

Authoritative and multifaceted, Gene Therapy for HIV and Chronic Infections is an ideal guide for researchers in the fields of gene therapy and immunology interested in expanding their knowledge on how to design an effective gene therapy against a viral pathogen.

Keywords

HIV chronic infections gene therapy gene transfer approaches hepatitis

Editors and affiliations

  • Ben Berkhout
    • 1
  • Hildegund C.J. Ertl
    • 2
  • Marc S. Weinberg
    • 3
  1. 1.University of AmsterdamAmsterdamThe Netherlands
  2. 2.The Wistar InstituteUniversity of PennsylvaniaPhiladelphiaUSA
  3. 3.University of the WitwatersrandJohannesburgSouth Africa

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-2432-5
  • Copyright Information American Society of Gene and Cell Therapy 2015
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-2431-8
  • Online ISBN 978-1-4939-2432-5
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • About this book
Industry Sectors
Biotechnology
Pharma