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Serotonin Receptor Technologies

  • Wolfgang Blenau
  • Arnd Baumann

Part of the Neuromethods book series (NM, volume 95)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Receptor Dimerization

    1. Front Matter
      Pages 1-1
    2. Sylwia Łukasiewicz, Ewa Błasiak, Kinga Szafran-Pilch, Marta Dziedzicka-Wasylewska
      Pages 3-20
    3. José L. Moreno, Jeremy Seto, James B. Hanks, Javier González-Maeso
      Pages 21-36
  3. Manipulation and Analysis of Serotonergic Signaling in Brain Slices

    1. Front Matter
      Pages 37-37
  4. Mouse Models to Study Serotonin-Associated Behavioral Disorders

    1. Front Matter
      Pages 57-57
    2. Robert Haberzettl, Heidrun Fink, Silke Dietze, Bettina Bert
      Pages 83-100
    3. Indira Mendez-David, Denis Joseph David, Jean-Philippe Guilloux, René Hen, Alain Michel Gardier
      Pages 101-121
  5. Serotonin Transporter

  6. Invertebrate Model Systems

  7. Back Matter
    Pages 241-245

About this book

Introduction

Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na+-dependent serotonin transporter (SERT), this volume provides state of the art methodologies currently applied in serotonin research from leading experts in the field. Serotonin Receptor Technologies describes approaches that vary from molecular biological and biochemical techniques (e.g., regarding receptor dimerization), fluorescence microscopy and imaging applications, flow cytometry, the use of organotypic slice and cell cultures to the generation of genetically modified animal models and the development of sophisticated behavioral tests, thus covering a wide spectrum of techniques to study serotonergic signaling in detail. Written for the popular Neuromethods series, chapters include the kind of detail and practical advice that ensures successful results in the lab.

Authoritative and convenient, Serotonin Receptor Technologies serves to foster both basic and translational research aiming to further deepen our understanding of the various facets of aminergic systems, as well as to aid research on similar problems with related GPCRs and neurotransmitter transporters.

Keywords

5-HT receptor subtypes Central nervous system (CNS) Drug action Na+-dependent serotonin transporter Neuropharmacology SERT Serotonergic system

Editors and affiliations

  • Wolfgang Blenau
    • 1
  • Arnd Baumann
    • 2
  1. 1.Universität zu KölnKölnGermany
  2. 2.Forschungszentrum JülichJülichGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-2187-4
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2186-7
  • Online ISBN 978-1-4939-2187-4
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site
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