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  • © 2014

How Helminths Alter Immunity to Infection

Editors:

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  • Reviews the current understanding of how helminth infections impact the ability to control unrelated infections

  • Covers new evidence about helminth infections controlling allergy and immune mechanisms

  • Examines helminth infections protecting against various auto-immune diseases

  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 828)

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USD 89.00
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  • ISBN: 978-1-4939-1489-0
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  • Tax calculation will be finalised during checkout
Softcover Book
USD 119.99
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Hardcover Book
USD 119.99
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Table of contents (6 chapters)

  1. Front Matter

    Pages i-x
  2. The Role of Antibody in Parasitic Helminth Infections

    • Erin Logan, Alisha Chetty, William G. Horsnell
    Pages 1-26
  3. Maternal Helminth Infections

    • Kathrin Straubinger, Clarissa Prazeres da Costa
    Pages 27-48
  4. Helminth-M. Tb Co-Infection

    • Nelita du Plessis, Gerhard Walzl
    Pages 49-74
  5. Bacterial Infections and Vaccines

    • Saeeda Bobat, Adam F. Cunningham
    Pages 75-98
  6. Helpful or a Hindrance: Co-infections with Helminths During Malaria

    • Laura E. Layland, Sabine Specht
    Pages 99-129
  7. Back Matter

    Pages 151-152

About this book

Helminth infections are common, cause considerable pathology, and alter a host’s immune profile. This can have important consequences not only on the host’s ability to control a helminth infection, but also on their ability to control unrelated infections. In endemic areas, understanding how helminth infection influences the outcome of common infectious diseases and changes the efficacy of childhood vaccination programs is an important public health question.

This book reviews how host immunity to helminths alters our ability to respond to the major pathogens that exist in helminth endemic regions. Current understanding of how helminths alter important but relatively neglected contributors to the host’s anti-helminth immune responses are addressed, namely host antibody responses and how maternal infection may alter a child’s immune development. These are discussed in relation to the control of helminth infection and unrelated infections. Also covered are how helminth infections alter the host’s ability to control TB, HIV and malarial infections along with neglected bacterial infections, such as cholera, and how endemic helminth infections are likely to alter our ability to respond to life-saving vaccination strategies.

Keywords

  • auto-immune disease
  • helminth
  • infections
  • infectious diseases

Editors and Affiliations

  • Division of Immunology/IIDM, University of Cape Town, Cape Town, South Africa

    William Horsnell

About the editor

William Horsnell is an immunologist at the University of Cape Town, South Africa. His research interests center on how parasitic helminth infections alter host immunity and the ability to control both the helminth and unrelated diseases.

Bibliographic Information

Buying options

eBook
USD 89.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-1489-0
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 119.99
Price excludes VAT (USA)
Hardcover Book
USD 119.99
Price excludes VAT (USA)