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  • © 2014

Mass Spectrometry in Metabolomics

Methods and Protocols

Editors:

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1198)

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Table of contents (22 protocols)

  1. Profiling Volatile Organic Compounds

    1. Front Matter

      Pages 249-249
  2. Profiling and Imaging Using Atomospheric Sampling Methods

    1. Front Matter

      Pages 273-273
    2. Metabolite Profiling by Direct Analysis in Real-Time Mass Spectrometry

      • Christina M. Jones, María Eugenia Monge, Facundo M. Fernández
      Pages 275-289
    3. Analysis of Dried Blood Spots Using DESI Mass Spectrometry

      • Justin M. Wiseman, Joseph H. Kennedy
      Pages 291-297
    4. Metabolic Imaging Using Nanostructure-Initiator Mass Spectrometry (NIMS)

      • Katherine B. Louie, Trent R. Northen
      Pages 313-329
  3. Statistical Analysis Methods

    1. Front Matter

      Pages 331-331
    2. Statistical Analysis and Modeling of Mass Spectrometry-Based Metabolomics Data

      • Bowei Xi, Haiwei Gu, Hamid Baniasadi, Daniel Raftery
      Pages 333-353
  4. Back Matter

    Pages 355-360

About this book

Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.

Editors and Affiliations

  • University of Washington Fred Hutchinson Cancer Rsrch Ctr, Seattle, USA

    Daniel Raftery

Bibliographic Information

  • Book Title: Mass Spectrometry in Metabolomics

  • Book Subtitle: Methods and Protocols

  • Editors: Daniel Raftery

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-1258-2

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4939-1257-5Published: 01 October 2014

  • Softcover ISBN: 978-1-4939-5319-6Published: 23 August 2016

  • eBook ISBN: 978-1-4939-1258-2Published: 01 October 2014

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XVI, 360

  • Number of Illustrations: 19 b/w illustrations, 52 illustrations in colour

  • Topics: Biochemistry, general, Biological Microscopy

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access