Neuroinflammation and Neurodegeneration

  • Phillip K. Peterson
  • Michal Toborek

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Mechanisms of Brain Defense and Neuropathogenesis

    1. Front Matter
      Pages 1-1
    2. Victor Castro, Michal Toborek
      Pages 3-28
    3. Beena John, Christopher A. Hunter, Tajie H. Harris
      Pages 29-45
    4. Alexei Verkhratsky, Mami Noda
      Pages 47-60
    5. Hui-Ming Gao, Hui Zhou, Jau-Shyong Hong
      Pages 81-104
  3. Neurological Diseases and Inflammation

    1. Front Matter
      Pages 117-117
    2. Mark R. Mizee, Gijs Kooij, Helga E. de Vries
      Pages 143-160
    3. Veronika M. Reinisch, Daniela L. Krause, Norbert Müller
      Pages 161-177
    4. Roland G. W. Staal, Thomas Möller
      Pages 179-197
    5. Mario Di Napoli, Craig J. Smith, Stephen J. Hopkins, Aurel Popa-Wagner, Ana Maria Buga, Mark Slevin
      Pages 199-244
  4. Infectious Diseases

    1. Front Matter
      Pages 245-245
    2. Kelly L. Stauch, Howard S. Fox
      Pages 247-262
    3. Mark R. Schleiss
      Pages 291-308
    4. G. von Geldern, M. J. Barhams, E. O. Major
      Pages 337-354
    5. Gregory Antell, Michael R. Nonnemacher, Vanessa Pirrone, Brian Wigdahl
      Pages 355-385
    6. Uwe Koedel, Matthias Klein, Hans-Walter Pfister
      Pages 387-404
    7. Gregory S. Park, Chandy C. John
      Pages 405-428
  5. Drugs of Abuse and NeuroAIDS

    1. Front Matter
      Pages 429-429
    2. Honghong Yao, Crystal Bethel-Brown, Shilpa J. Buch
      Pages 431-442
    3. Nicole A. Northrop, Bryan K. Yamamoto
      Pages 443-462
    4. Thomas J. Rogers
      Pages 463-486
    5. Paige S. Katz, Scott Edwards, Patricia E. Molina
      Pages 487-510
    6. Yuri Persidsky, Larisa Gofman, Raghava Potula
      Pages 511-526
  6. Novel Approaches to Therapy

    1. Front Matter
      Pages 527-527
    2. JoEllyn M. McMillan, Howard E. Gendelman
      Pages 529-546
    3. David J. Graber, William F. Hickey
      Pages 547-567
    4. Guy A. Cabral, Melissa Jamerson
      Pages 569-587
  7. Back Matter
    Pages 589-600

About this book


State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases, and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration).  Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitis, and substance abuse.  In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system.   With rare exception, no or inadequate treatment exists for the diseases discussed in this book.  An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.


Alzheimer's Disease Multiple Sclerosis Parkinson's Disease neurodegeneration neuroinflammation substances of abuse

Editors and affiliations

  • Phillip K. Peterson
    • 1
  • Michal Toborek
    • 2
  1. 1.Department of MedicineUniversity of Minnesota Medical SchoolMinneapolisUSA
  2. 2.Department of Biochemistry Department of Molecular BiologyUniversity of Miami School of MedicineMiamiUSA

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