Neuroinflammation and Neurodegeneration

  • Phillip K. Peterson
  • Michal Toborek

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Mechanisms of Brain Defense and Neuropathogenesis

    1. Front Matter
      Pages 1-1
    2. Victor Castro, Michal Toborek
      Pages 3-28
    3. Beena John, Christopher A. Hunter, Tajie H. Harris
      Pages 29-45
    4. Alexei Verkhratsky, Mami Noda
      Pages 47-60
    5. Hui-Ming Gao, Hui Zhou, Jau-Shyong Hong
      Pages 81-104
  3. Neurological Diseases and Inflammation

    1. Front Matter
      Pages 117-117
    2. Mark R. Mizee, Gijs Kooij, Helga E. de Vries
      Pages 143-160
    3. Veronika M. Reinisch, Daniela L. Krause, Norbert Müller
      Pages 161-177
    4. Roland G. W. Staal, Thomas Möller
      Pages 179-197
    5. Mario Di Napoli, Craig J. Smith, Stephen J. Hopkins, Aurel Popa-Wagner, Ana Maria Buga, Mark Slevin
      Pages 199-244
  4. Infectious Diseases

    1. Front Matter
      Pages 245-245
    2. Kelly L. Stauch, Howard S. Fox
      Pages 247-262
    3. Mark R. Schleiss
      Pages 291-308
    4. G. von Geldern, M. J. Barhams, E. O. Major
      Pages 337-354

About this book


State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases, and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration).  Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitis, and substance abuse.  In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system.   With rare exception, no or inadequate treatment exists for the diseases discussed in this book.  An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.


Alzheimer's Disease Multiple Sclerosis Parkinson's Disease neurodegeneration neuroinflammation substances of abuse

Editors and affiliations

  • Phillip K. Peterson
    • 1
  • Michal Toborek
    • 2
  1. 1.Department of MedicineUniversity of Minnesota Medical SchoolMinneapolisUSA
  2. 2.Department of Biochemistry Department of Molecular BiologyUniversity of Miami School of MedicineMiamiUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2014
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-1070-0
  • Online ISBN 978-1-4939-1071-7
  • About this book
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