Genes and the Motivation to Use Substances

  • Scott F. Stoltenberg

Part of the Nebraska Symposium on Motivation book series (NSM, volume 61)

Table of contents

About this book


Human beings have been using intoxicating substances for millennia. But while most people have used psychoactive substances without becoming dependent on them, a significant minority develop substance use disorders. The question remains: why does addiction occur in some and not others?

The 61st installment of the Nebraska Symposium on Motivation, Genes and the Motivation to Use Substances probes the complex role of genetics in substance use and abuse across diverse methodologies, research organisms, levels of analysis, and disciplines. Its combined lifespan/motivation approach to individual differences sheds necessary light on genetic vs. environmental factors in vulnerability, addiction risk, the relationship between behavioral disinhibition and substance use, and the motivation to quit. While alcohol use/abuse is the focus of much of the book, its chapters provide scientific and clinical insights into substance abuse in general as well as implications for treatment. And an intriguing conclusion discusses  the need to bridge the gap between genetics and neuroscience, and the best scientific conditions in which this integration may thrive. Included in the coverage:

  • Rodent models of genetic contributions to the motivation to use alcohol.
  • The adolescent origins of substance abuse disorders
  • The developmental matrix of addictive behavior
  • The genetics of cannabis involvement
  • The DNA methylation signature of smoking
  • Genomics of impulsivity: integrating genetics and neuroscience.

Reflecting the current state of knowledge in a field with groundbreaking potential, Genes and the Motivation to Use Substances is a fascinating resource for psychologists, psychiatrists, geneticists, neuroscientists, social workers, policymakers, and researchers in addiction.


gene expression genes and addiction genes and substance abuse genetics and addiction treatment genetics and substance abuse motivation and addiction

Editors and affiliations

  • Scott F. Stoltenberg
    • 1
  1. 1.PsychologyUniversity of Nebraska-LincolnLincolnUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2014
  • Publisher Name Springer, New York, NY
  • eBook Packages Behavioral Science
  • Print ISBN 978-1-4939-0652-9
  • Online ISBN 978-1-4939-0653-6
  • Series Print ISSN 0146-7875
  • Buy this book on publisher's site